5INF

Structural basis for acyl-CoA carboxylase-mediated assembly of unusual polyketide synthase extender units incorporated into the stambomycin antibiotics

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003989	molecular_function	acetyl-CoA carboxylase activity
A	0004658	molecular_function	propionyl-CoA carboxylase activity
A	0006633	biological_process	fatty acid biosynthetic process
A	0009317	cellular_component	acetyl-CoA carboxylase complex
A	0016740	molecular_function	transferase activity
A	0016874	molecular_function	ligase activity
B	0003989	molecular_function	acetyl-CoA carboxylase activity
B	0004658	molecular_function	propionyl-CoA carboxylase activity
B	0006633	biological_process	fatty acid biosynthetic process
B	0009317	cellular_component	acetyl-CoA carboxylase complex
B	0016740	molecular_function	transferase activity
B	0016874	molecular_function	ligase activity
C	0003989	molecular_function	acetyl-CoA carboxylase activity
C	0004658	molecular_function	propionyl-CoA carboxylase activity
C	0006633	biological_process	fatty acid biosynthetic process
C	0009317	cellular_component	acetyl-CoA carboxylase complex
C	0016740	molecular_function	transferase activity
C	0016874	molecular_function	ligase activity
D	0003989	molecular_function	acetyl-CoA carboxylase activity
D	0004658	molecular_function	propionyl-CoA carboxylase activity
D	0006633	biological_process	fatty acid biosynthetic process
D	0009317	cellular_component	acetyl-CoA carboxylase complex
D	0016740	molecular_function	transferase activity
D	0016874	molecular_function	ligase activity
E	0003989	molecular_function	acetyl-CoA carboxylase activity
E	0004658	molecular_function	propionyl-CoA carboxylase activity
E	0006633	biological_process	fatty acid biosynthetic process
E	0009317	cellular_component	acetyl-CoA carboxylase complex
E	0016740	molecular_function	transferase activity
E	0016874	molecular_function	ligase activity
F	0003989	molecular_function	acetyl-CoA carboxylase activity
F	0004658	molecular_function	propionyl-CoA carboxylase activity
F	0006633	biological_process	fatty acid biosynthetic process
F	0009317	cellular_component	acetyl-CoA carboxylase complex
F	0016740	molecular_function	transferase activity
F	0016874	molecular_function	ligase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	21
Details	binding site for residue HXC B 601

Chain	Residue
B	LEU110
B	GLY161
B	GLY183
B	GLY184
B	TYR187
B	GLY208
B	GLU210
B	HOH738
B	HOH813
F	PHE399
F	GLY419
B	GLY111
F	GLY420
F	PRO453
B	GLY143
B	GLY144
B	ALA145
B	ARG146
B	ILE147
B	GLN148
B	TYR157

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