5IKD
Asymmetric sulfoxidation by engineering the heme pocket of a dye-decolorizing peroxidase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005829 | cellular_component | cytosol |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0020037 | molecular_function | heme binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| A | 0140825 | molecular_function | lactoperoxidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue HEM A 501 |
| Chain | Residue |
| A | GLU162 |
| A | ILE305 |
| A | THR308 |
| A | ARG309 |
| A | ARG311 |
| A | ARG332 |
| A | PHE370 |
| A | ILE398 |
| A | HOH610 |
| A | HOH697 |
| A | HOH701 |
| A | PHE166 |
| A | HOH730 |
| A | HOH918 |
| A | LEU167 |
| A | GLY169 |
| A | ILE170 |
| A | ALA171 |
| A | GLN221 |
| A | ARG255 |
| A | HIS304 |
Functional Information from PROSITE/UniProt
| site_id | PS00059 |
| Number of Residues | 15 |
| Details | ADH_ZINC Zinc-containing alcohol dehydrogenases signature. GHEmFGFldgiAqpA |
| Chain | Residue | Details |
| A | GLY160-ALA174 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"23235158","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"23235158","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25495127","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25542606","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"journal article","publicationDate":"2016","firstPage":"6277","lastPage":"6285","volume":"6","journal":"Catal. Sci. Technol.","title":"Asymmetric sulfoxidation by engineering the heme pocket of a dye-decolorizing peroxidase.","authors":["Linde D.","Canellas M.","Davo-Siguero I.","Romero A.","Lucas F.","Ruiz-Duenas F.J.","Guallar V.","Martinez A.T."],"citationCrossReferences":[{"database":"DOI","id":"10.1039/c6cy00539j"}]}},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JAN-2015","submissionDatabase":"PDB data bank","title":"Crystallographic Trapping of a Covalently Modified Heme in a Dye-Decolorizing Peroxidase.","authors":["Strittmatter E.","Piontek K.","Plattner D.A."]}},{"source":"PDB","id":"4AU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4UZI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4W7J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4W7K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4W7L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4W7M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4W7N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4W7O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5IKD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5IKG","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"23235158","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25542606","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JAN-2015","submissionDatabase":"PDB data bank","title":"Crystallographic Trapping of a Covalently Modified Heme in a Dye-Decolorizing Peroxidase.","authors":["Strittmatter E.","Piontek K.","Plattner D.A."]}},{"source":"PDB","id":"4AU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4UZI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AG1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00498","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
