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5IJO

Alternative composite structure of the inner ring of the human nuclear pore complex (16 copies of Nup188, 16 copies of Nup205)

Functional Information from GO Data
ChainGOidnamespacecontents
A0000972biological_processtranscription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005635cellular_componentnuclear envelope
A0005643cellular_componentnuclear pore
A0005829cellular_componentcytosol
A0006405biological_processRNA export from nucleus
A0006406biological_processmRNA export from nucleus
A0006606biological_processprotein import into nucleus
A0006913biological_processnucleocytoplasmic transport
A0006998biological_processnuclear envelope organization
A0015031biological_processprotein transport
A0016020cellular_componentmembrane
A0017056molecular_functionstructural constituent of nuclear pore
A0031965cellular_componentnuclear membrane
A0034504biological_processprotein localization to nucleus
A0035196biological_processmiRNA processing
A0036228biological_processprotein localization to nuclear inner membrane
A0044611cellular_componentnuclear pore inner ring
A0051028biological_processmRNA transport
A0086014biological_processatrial cardiac muscle cell action potential
B0000972biological_processtranscription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005635cellular_componentnuclear envelope
B0005643cellular_componentnuclear pore
B0005829cellular_componentcytosol
B0006405biological_processRNA export from nucleus
B0006406biological_processmRNA export from nucleus
B0006606biological_processprotein import into nucleus
B0006913biological_processnucleocytoplasmic transport
B0006998biological_processnuclear envelope organization
B0015031biological_processprotein transport
B0016020cellular_componentmembrane
B0017056molecular_functionstructural constituent of nuclear pore
B0031965cellular_componentnuclear membrane
B0034504biological_processprotein localization to nucleus
B0035196biological_processmiRNA processing
B0036228biological_processprotein localization to nuclear inner membrane
B0044611cellular_componentnuclear pore inner ring
B0051028biological_processmRNA transport
B0086014biological_processatrial cardiac muscle cell action potential
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005635cellular_componentnuclear envelope
C0005643cellular_componentnuclear pore
C0005813cellular_componentcentrosome
C0005829cellular_componentcytosol
C0006606biological_processprotein import into nucleus
C0006913biological_processnucleocytoplasmic transport
C0006998biological_processnuclear envelope organization
C0015031biological_processprotein transport
C0016020cellular_componentmembrane
C0016973biological_processpoly(A)+ mRNA export from nucleus
C0017056molecular_functionstructural constituent of nuclear pore
C0031965cellular_componentnuclear membrane
C0034399cellular_componentnuclear periphery
C0051028biological_processmRNA transport
C0051292biological_processnuclear pore complex assembly
C0060391biological_processpositive regulation of SMAD protein signal transduction
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005635cellular_componentnuclear envelope
D0005643cellular_componentnuclear pore
D0005829cellular_componentcytosol
D0006913biological_processnucleocytoplasmic transport
D0006999biological_processnuclear pore organization
D0015031biological_processprotein transport
D0016020cellular_componentmembrane
D0017056molecular_functionstructural constituent of nuclear pore
D0031965cellular_componentnuclear membrane
D0034399cellular_componentnuclear periphery
D0044611cellular_componentnuclear pore inner ring
D0051028biological_processmRNA transport
D0051292biological_processnuclear pore complex assembly
E0000972biological_processtranscription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0005635cellular_componentnuclear envelope
E0005643cellular_componentnuclear pore
E0005829cellular_componentcytosol
E0006405biological_processRNA export from nucleus
E0006406biological_processmRNA export from nucleus
E0006606biological_processprotein import into nucleus
E0006913biological_processnucleocytoplasmic transport
E0006998biological_processnuclear envelope organization
E0015031biological_processprotein transport
E0016020cellular_componentmembrane
E0017056molecular_functionstructural constituent of nuclear pore
E0031965cellular_componentnuclear membrane
E0034504biological_processprotein localization to nucleus
E0035196biological_processmiRNA processing
E0036228biological_processprotein localization to nuclear inner membrane
E0044611cellular_componentnuclear pore inner ring
E0051028biological_processmRNA transport
E0086014biological_processatrial cardiac muscle cell action potential
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0005635cellular_componentnuclear envelope
F0005643cellular_componentnuclear pore
F0006605biological_processprotein targeting
F0006607biological_processNLS-bearing protein import into nucleus
F0006913biological_processnucleocytoplasmic transport
F0006999biological_processnuclear pore organization
F0015031biological_processprotein transport
F0016020cellular_componentmembrane
F0017056molecular_functionstructural constituent of nuclear pore
F0031965cellular_componentnuclear membrane
F0032991cellular_componentprotein-containing complex
F0036228biological_processprotein localization to nuclear inner membrane
F0042306biological_processregulation of protein import into nucleus
F0042802molecular_functionidentical protein binding
F0044613cellular_componentnuclear pore central transport channel
F0044877molecular_functionprotein-containing complex binding
F0051028biological_processmRNA transport
G0005515molecular_functionprotein binding
G0005634cellular_componentnucleus
G0005635cellular_componentnuclear envelope
G0005643cellular_componentnuclear pore
G0006913biological_processnucleocytoplasmic transport
G0008139molecular_functionnuclear localization sequence binding
G0015031biological_processprotein transport
G0016020cellular_componentmembrane
G0017056molecular_functionstructural constituent of nuclear pore
G0031965cellular_componentnuclear membrane
G0032991cellular_componentprotein-containing complex
G0042306biological_processregulation of protein import into nucleus
G0042802molecular_functionidentical protein binding
G0044877molecular_functionprotein-containing complex binding
G0051028biological_processmRNA transport
H0000922cellular_componentspindle pole
H0003682molecular_functionchromatin binding
H0005515molecular_functionprotein binding
H0005543molecular_functionphospholipid binding
H0005634cellular_componentnucleus
H0005635cellular_componentnuclear envelope
H0005643cellular_componentnuclear pore
H0005654cellular_componentnucleoplasm
H0005737cellular_componentcytoplasm
H0005813cellular_componentcentrosome
H0005856cellular_componentcytoskeleton
H0006405biological_processRNA export from nucleus
H0006606biological_processprotein import into nucleus
H0006913biological_processnucleocytoplasmic transport
H0007080biological_processmitotic metaphase chromosome alignment
H0007098biological_processcentrosome cycle
H0007100biological_processmitotic centrosome separation
H0007166biological_processcell surface receptor signaling pathway
H0008285biological_processnegative regulation of cell population proliferation
H0009966biological_processregulation of signal transduction
H0015031biological_processprotein transport
H0017056molecular_functionstructural constituent of nuclear pore
H0030159molecular_functionsignaling receptor complex adaptor activity
H0030544molecular_functionHsp70 protein binding
H0031965cellular_componentnuclear membrane
H0042059biological_processnegative regulation of epidermal growth factor receptor signaling pathway
H0042169molecular_functionSH2 domain binding
H0043066biological_processnegative regulation of apoptotic process
H0043069biological_processnegative regulation of programmed cell death
H0043123biological_processpositive regulation of canonical NF-kappaB signal transduction
H0043130molecular_functionubiquitin binding
H0043407biological_processnegative regulation of MAP kinase activity
H0044613cellular_componentnuclear pore central transport channel
H0045742biological_processpositive regulation of epidermal growth factor receptor signaling pathway
H0045840biological_processpositive regulation of mitotic nuclear division
H0045893biological_processpositive regulation of DNA-templated transcription
H0046578biological_processregulation of Ras protein signal transduction
H0046580biological_processnegative regulation of Ras protein signal transduction
H0046601biological_processpositive regulation of centriole replication
H0051028biological_processmRNA transport
H0051425molecular_functionPTB domain binding
H0051879molecular_functionHsp90 protein binding
H0060236biological_processregulation of mitotic spindle organization
H0072686cellular_componentmitotic spindle
H0090398biological_processcellular senescence
H0090543cellular_componentFlemming body
H0098534biological_processcentriole assembly
H1903438biological_processpositive regulation of mitotic cytokinetic process
H1904781biological_processpositive regulation of protein localization to centrosome
H1990904cellular_componentribonucleoprotein complex
I0005515molecular_functionprotein binding
I0005634cellular_componentnucleus
I0005635cellular_componentnuclear envelope
I0005643cellular_componentnuclear pore
I0005813cellular_componentcentrosome
I0005829cellular_componentcytosol
I0006606biological_processprotein import into nucleus
I0006913biological_processnucleocytoplasmic transport
I0006998biological_processnuclear envelope organization
I0015031biological_processprotein transport
I0016020cellular_componentmembrane
I0016973biological_processpoly(A)+ mRNA export from nucleus
I0017056molecular_functionstructural constituent of nuclear pore
I0031965cellular_componentnuclear membrane
I0034399cellular_componentnuclear periphery
I0051028biological_processmRNA transport
I0051292biological_processnuclear pore complex assembly
I0060391biological_processpositive regulation of SMAD protein signal transduction
J0005634cellular_componentnucleus
J0005635cellular_componentnuclear envelope
J0005643cellular_componentnuclear pore
J0005829cellular_componentcytosol
J0006405biological_processRNA export from nucleus
J0006606biological_processprotein import into nucleus
J0006913biological_processnucleocytoplasmic transport
J0015031biological_processprotein transport
J0016020cellular_componentmembrane
J0017056molecular_functionstructural constituent of nuclear pore
J0044611cellular_componentnuclear pore inner ring
J0051028biological_processmRNA transport
K0000972biological_processtranscription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
K0005515molecular_functionprotein binding
K0005634cellular_componentnucleus
K0005635cellular_componentnuclear envelope
K0005643cellular_componentnuclear pore
K0005829cellular_componentcytosol
K0006405biological_processRNA export from nucleus
K0006406biological_processmRNA export from nucleus
K0006606biological_processprotein import into nucleus
K0006913biological_processnucleocytoplasmic transport
K0006998biological_processnuclear envelope organization
K0015031biological_processprotein transport
K0016020cellular_componentmembrane
K0017056molecular_functionstructural constituent of nuclear pore
K0031965cellular_componentnuclear membrane
K0034504biological_processprotein localization to nucleus
K0035196biological_processmiRNA processing
K0036228biological_processprotein localization to nuclear inner membrane
K0044611cellular_componentnuclear pore inner ring
K0051028biological_processmRNA transport
K0086014biological_processatrial cardiac muscle cell action potential
L0005515molecular_functionprotein binding
L0005634cellular_componentnucleus
L0005635cellular_componentnuclear envelope
L0005643cellular_componentnuclear pore
L0006605biological_processprotein targeting
L0006607biological_processNLS-bearing protein import into nucleus
L0006913biological_processnucleocytoplasmic transport
L0006999biological_processnuclear pore organization
L0015031biological_processprotein transport
L0016020cellular_componentmembrane
L0017056molecular_functionstructural constituent of nuclear pore
L0031965cellular_componentnuclear membrane
L0032991cellular_componentprotein-containing complex
L0036228biological_processprotein localization to nuclear inner membrane
L0042306biological_processregulation of protein import into nucleus
L0042802molecular_functionidentical protein binding
L0044613cellular_componentnuclear pore central transport channel
L0044877molecular_functionprotein-containing complex binding
L0051028biological_processmRNA transport
M0005515molecular_functionprotein binding
M0005634cellular_componentnucleus
M0005635cellular_componentnuclear envelope
M0005643cellular_componentnuclear pore
M0006913biological_processnucleocytoplasmic transport
M0008139molecular_functionnuclear localization sequence binding
M0015031biological_processprotein transport
M0016020cellular_componentmembrane
M0017056molecular_functionstructural constituent of nuclear pore
M0031965cellular_componentnuclear membrane
M0032991cellular_componentprotein-containing complex
M0042306biological_processregulation of protein import into nucleus
M0042802molecular_functionidentical protein binding
M0044877molecular_functionprotein-containing complex binding
M0051028biological_processmRNA transport
N0000922cellular_componentspindle pole
N0003682molecular_functionchromatin binding
N0005515molecular_functionprotein binding
N0005543molecular_functionphospholipid binding
N0005634cellular_componentnucleus
N0005635cellular_componentnuclear envelope
N0005643cellular_componentnuclear pore
N0005654cellular_componentnucleoplasm
N0005737cellular_componentcytoplasm
N0005813cellular_componentcentrosome
N0005856cellular_componentcytoskeleton
N0006405biological_processRNA export from nucleus
N0006606biological_processprotein import into nucleus
N0006913biological_processnucleocytoplasmic transport
N0007080biological_processmitotic metaphase chromosome alignment
N0007098biological_processcentrosome cycle
N0007100biological_processmitotic centrosome separation
N0007166biological_processcell surface receptor signaling pathway
N0008285biological_processnegative regulation of cell population proliferation
N0009966biological_processregulation of signal transduction
N0015031biological_processprotein transport
N0017056molecular_functionstructural constituent of nuclear pore
N0030159molecular_functionsignaling receptor complex adaptor activity
N0030544molecular_functionHsp70 protein binding
N0031965cellular_componentnuclear membrane
N0042059biological_processnegative regulation of epidermal growth factor receptor signaling pathway
N0042169molecular_functionSH2 domain binding
N0043066biological_processnegative regulation of apoptotic process
N0043069biological_processnegative regulation of programmed cell death
N0043123biological_processpositive regulation of canonical NF-kappaB signal transduction
N0043130molecular_functionubiquitin binding
N0043407biological_processnegative regulation of MAP kinase activity
N0044613cellular_componentnuclear pore central transport channel
N0045742biological_processpositive regulation of epidermal growth factor receptor signaling pathway
N0045840biological_processpositive regulation of mitotic nuclear division
N0045893biological_processpositive regulation of DNA-templated transcription
N0046578biological_processregulation of Ras protein signal transduction
N0046580biological_processnegative regulation of Ras protein signal transduction
N0046601biological_processpositive regulation of centriole replication
N0051028biological_processmRNA transport
N0051425molecular_functionPTB domain binding
N0051879molecular_functionHsp90 protein binding
N0060236biological_processregulation of mitotic spindle organization
N0072686cellular_componentmitotic spindle
N0090398biological_processcellular senescence
N0090543cellular_componentFlemming body
N0098534biological_processcentriole assembly
N1903438biological_processpositive regulation of mitotic cytokinetic process
N1904781biological_processpositive regulation of protein localization to centrosome
N1990904cellular_componentribonucleoprotein complex
O0005515molecular_functionprotein binding
O0005634cellular_componentnucleus
O0005635cellular_componentnuclear envelope
O0005643cellular_componentnuclear pore
O0005813cellular_componentcentrosome
O0005829cellular_componentcytosol
O0006606biological_processprotein import into nucleus
O0006913biological_processnucleocytoplasmic transport
O0006998biological_processnuclear envelope organization
O0015031biological_processprotein transport
O0016020cellular_componentmembrane
O0016973biological_processpoly(A)+ mRNA export from nucleus
O0017056molecular_functionstructural constituent of nuclear pore
O0031965cellular_componentnuclear membrane
O0034399cellular_componentnuclear periphery
O0051028biological_processmRNA transport
O0051292biological_processnuclear pore complex assembly
O0060391biological_processpositive regulation of SMAD protein signal transduction
P0005515molecular_functionprotein binding
P0005634cellular_componentnucleus
P0005635cellular_componentnuclear envelope
P0005643cellular_componentnuclear pore
P0005829cellular_componentcytosol
P0006913biological_processnucleocytoplasmic transport
P0006999biological_processnuclear pore organization
P0015031biological_processprotein transport
P0016020cellular_componentmembrane
P0017056molecular_functionstructural constituent of nuclear pore
P0031965cellular_componentnuclear membrane
P0034399cellular_componentnuclear periphery
P0044611cellular_componentnuclear pore inner ring
P0051028biological_processmRNA transport
P0051292biological_processnuclear pore complex assembly
Q0000972biological_processtranscription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
Q0005515molecular_functionprotein binding
Q0005634cellular_componentnucleus
Q0005635cellular_componentnuclear envelope
Q0005643cellular_componentnuclear pore
Q0005829cellular_componentcytosol
Q0006405biological_processRNA export from nucleus
Q0006406biological_processmRNA export from nucleus
Q0006606biological_processprotein import into nucleus
Q0006913biological_processnucleocytoplasmic transport
Q0006998biological_processnuclear envelope organization
Q0015031biological_processprotein transport
Q0016020cellular_componentmembrane
Q0017056molecular_functionstructural constituent of nuclear pore
Q0031965cellular_componentnuclear membrane
Q0034504biological_processprotein localization to nucleus
Q0035196biological_processmiRNA processing
Q0036228biological_processprotein localization to nuclear inner membrane
Q0044611cellular_componentnuclear pore inner ring
Q0051028biological_processmRNA transport
Q0086014biological_processatrial cardiac muscle cell action potential
R0005515molecular_functionprotein binding
R0005634cellular_componentnucleus
R0005635cellular_componentnuclear envelope
R0005643cellular_componentnuclear pore
R0006605biological_processprotein targeting
R0006607biological_processNLS-bearing protein import into nucleus
R0006913biological_processnucleocytoplasmic transport
R0006999biological_processnuclear pore organization
R0015031biological_processprotein transport
R0016020cellular_componentmembrane
R0017056molecular_functionstructural constituent of nuclear pore
R0031965cellular_componentnuclear membrane
R0032991cellular_componentprotein-containing complex
R0036228biological_processprotein localization to nuclear inner membrane
R0042306biological_processregulation of protein import into nucleus
R0042802molecular_functionidentical protein binding
R0044613cellular_componentnuclear pore central transport channel
R0044877molecular_functionprotein-containing complex binding
R0051028biological_processmRNA transport
S0005515molecular_functionprotein binding
S0005634cellular_componentnucleus
S0005635cellular_componentnuclear envelope
S0005643cellular_componentnuclear pore
S0006913biological_processnucleocytoplasmic transport
S0008139molecular_functionnuclear localization sequence binding
S0015031biological_processprotein transport
S0016020cellular_componentmembrane
S0017056molecular_functionstructural constituent of nuclear pore
S0031965cellular_componentnuclear membrane
S0032991cellular_componentprotein-containing complex
S0042306biological_processregulation of protein import into nucleus
S0042802molecular_functionidentical protein binding
S0044877molecular_functionprotein-containing complex binding
S0051028biological_processmRNA transport
T0000922cellular_componentspindle pole
T0003682molecular_functionchromatin binding
T0005515molecular_functionprotein binding
T0005543molecular_functionphospholipid binding
T0005634cellular_componentnucleus
T0005635cellular_componentnuclear envelope
T0005643cellular_componentnuclear pore
T0005654cellular_componentnucleoplasm
T0005737cellular_componentcytoplasm
T0005813cellular_componentcentrosome
T0005856cellular_componentcytoskeleton
T0006405biological_processRNA export from nucleus
T0006606biological_processprotein import into nucleus
T0006913biological_processnucleocytoplasmic transport
T0007080biological_processmitotic metaphase chromosome alignment
T0007098biological_processcentrosome cycle
T0007100biological_processmitotic centrosome separation
T0007166biological_processcell surface receptor signaling pathway
T0008285biological_processnegative regulation of cell population proliferation
T0009966biological_processregulation of signal transduction
T0015031biological_processprotein transport
T0017056molecular_functionstructural constituent of nuclear pore
T0030159molecular_functionsignaling receptor complex adaptor activity
T0030544molecular_functionHsp70 protein binding
T0031965cellular_componentnuclear membrane
T0042059biological_processnegative regulation of epidermal growth factor receptor signaling pathway
T0042169molecular_functionSH2 domain binding
T0043066biological_processnegative regulation of apoptotic process
T0043069biological_processnegative regulation of programmed cell death
T0043123biological_processpositive regulation of canonical NF-kappaB signal transduction
T0043130molecular_functionubiquitin binding
T0043407biological_processnegative regulation of MAP kinase activity
T0044613cellular_componentnuclear pore central transport channel
T0045742biological_processpositive regulation of epidermal growth factor receptor signaling pathway
T0045840biological_processpositive regulation of mitotic nuclear division
T0045893biological_processpositive regulation of DNA-templated transcription
T0046578biological_processregulation of Ras protein signal transduction
T0046580biological_processnegative regulation of Ras protein signal transduction
T0046601biological_processpositive regulation of centriole replication
T0051028biological_processmRNA transport
T0051425molecular_functionPTB domain binding
T0051879molecular_functionHsp90 protein binding
T0060236biological_processregulation of mitotic spindle organization
T0072686cellular_componentmitotic spindle
T0090398biological_processcellular senescence
T0090543cellular_componentFlemming body
T0098534biological_processcentriole assembly
T1903438biological_processpositive regulation of mitotic cytokinetic process
T1904781biological_processpositive regulation of protein localization to centrosome
T1990904cellular_componentribonucleoprotein complex
U0005515molecular_functionprotein binding
U0005634cellular_componentnucleus
U0005635cellular_componentnuclear envelope
U0005643cellular_componentnuclear pore
U0005813cellular_componentcentrosome
U0005829cellular_componentcytosol
U0006606biological_processprotein import into nucleus
U0006913biological_processnucleocytoplasmic transport
U0006998biological_processnuclear envelope organization
U0015031biological_processprotein transport
U0016020cellular_componentmembrane
U0016973biological_processpoly(A)+ mRNA export from nucleus
U0017056molecular_functionstructural constituent of nuclear pore
U0031965cellular_componentnuclear membrane
U0034399cellular_componentnuclear periphery
U0051028biological_processmRNA transport
U0051292biological_processnuclear pore complex assembly
U0060391biological_processpositive regulation of SMAD protein signal transduction
V0005634cellular_componentnucleus
V0005635cellular_componentnuclear envelope
V0005643cellular_componentnuclear pore
V0005829cellular_componentcytosol
V0006405biological_processRNA export from nucleus
V0006606biological_processprotein import into nucleus
V0006913biological_processnucleocytoplasmic transport
V0015031biological_processprotein transport
V0016020cellular_componentmembrane
V0017056molecular_functionstructural constituent of nuclear pore
V0044611cellular_componentnuclear pore inner ring
V0051028biological_processmRNA transport
W0000972biological_processtranscription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
W0005515molecular_functionprotein binding
W0005634cellular_componentnucleus
W0005635cellular_componentnuclear envelope
W0005643cellular_componentnuclear pore
W0005829cellular_componentcytosol
W0006405biological_processRNA export from nucleus
W0006406biological_processmRNA export from nucleus
W0006606biological_processprotein import into nucleus
W0006913biological_processnucleocytoplasmic transport
W0006998biological_processnuclear envelope organization
W0015031biological_processprotein transport
W0016020cellular_componentmembrane
W0017056molecular_functionstructural constituent of nuclear pore
W0031965cellular_componentnuclear membrane
W0034504biological_processprotein localization to nucleus
W0035196biological_processmiRNA processing
W0036228biological_processprotein localization to nuclear inner membrane
W0044611cellular_componentnuclear pore inner ring
W0051028biological_processmRNA transport
W0086014biological_processatrial cardiac muscle cell action potential
X0005515molecular_functionprotein binding
X0005634cellular_componentnucleus
X0005635cellular_componentnuclear envelope
X0005643cellular_componentnuclear pore
X0006605biological_processprotein targeting
X0006607biological_processNLS-bearing protein import into nucleus
X0006913biological_processnucleocytoplasmic transport
X0006999biological_processnuclear pore organization
X0015031biological_processprotein transport
X0016020cellular_componentmembrane
X0017056molecular_functionstructural constituent of nuclear pore
X0031965cellular_componentnuclear membrane
X0032991cellular_componentprotein-containing complex
X0036228biological_processprotein localization to nuclear inner membrane
X0042306biological_processregulation of protein import into nucleus
X0042802molecular_functionidentical protein binding
X0044613cellular_componentnuclear pore central transport channel
X0044877molecular_functionprotein-containing complex binding
X0051028biological_processmRNA transport
Y0005515molecular_functionprotein binding
Y0005634cellular_componentnucleus
Y0005635cellular_componentnuclear envelope
Y0005643cellular_componentnuclear pore
Y0006913biological_processnucleocytoplasmic transport
Y0008139molecular_functionnuclear localization sequence binding
Y0015031biological_processprotein transport
Y0016020cellular_componentmembrane
Y0017056molecular_functionstructural constituent of nuclear pore
Y0031965cellular_componentnuclear membrane
Y0032991cellular_componentprotein-containing complex
Y0042306biological_processregulation of protein import into nucleus
Y0042802molecular_functionidentical protein binding
Y0044877molecular_functionprotein-containing complex binding
Y0051028biological_processmRNA transport
Z0000922cellular_componentspindle pole
Z0003682molecular_functionchromatin binding
Z0005515molecular_functionprotein binding
Z0005543molecular_functionphospholipid binding
Z0005634cellular_componentnucleus
Z0005635cellular_componentnuclear envelope
Z0005643cellular_componentnuclear pore
Z0005654cellular_componentnucleoplasm
Z0005737cellular_componentcytoplasm
Z0005813cellular_componentcentrosome
Z0005856cellular_componentcytoskeleton
Z0006405biological_processRNA export from nucleus
Z0006606biological_processprotein import into nucleus
Z0006913biological_processnucleocytoplasmic transport
Z0007080biological_processmitotic metaphase chromosome alignment
Z0007098biological_processcentrosome cycle
Z0007100biological_processmitotic centrosome separation
Z0007166biological_processcell surface receptor signaling pathway
Z0008285biological_processnegative regulation of cell population proliferation
Z0009966biological_processregulation of signal transduction
Z0015031biological_processprotein transport
Z0017056molecular_functionstructural constituent of nuclear pore
Z0030159molecular_functionsignaling receptor complex adaptor activity
Z0030544molecular_functionHsp70 protein binding
Z0031965cellular_componentnuclear membrane
Z0042059biological_processnegative regulation of epidermal growth factor receptor signaling pathway
Z0042169molecular_functionSH2 domain binding
Z0043066biological_processnegative regulation of apoptotic process
Z0043069biological_processnegative regulation of programmed cell death
Z0043123biological_processpositive regulation of canonical NF-kappaB signal transduction
Z0043130molecular_functionubiquitin binding
Z0043407biological_processnegative regulation of MAP kinase activity
Z0044613cellular_componentnuclear pore central transport channel
Z0045742biological_processpositive regulation of epidermal growth factor receptor signaling pathway
Z0045840biological_processpositive regulation of mitotic nuclear division
Z0045893biological_processpositive regulation of DNA-templated transcription
Z0046578biological_processregulation of Ras protein signal transduction
Z0046580biological_processnegative regulation of Ras protein signal transduction
Z0046601biological_processpositive regulation of centriole replication
Z0051028biological_processmRNA transport
Z0051425molecular_functionPTB domain binding
Z0051879molecular_functionHsp90 protein binding
Z0060236biological_processregulation of mitotic spindle organization
Z0072686cellular_componentmitotic spindle
Z0090398biological_processcellular senescence
Z0090543cellular_componentFlemming body
Z0098534biological_processcentriole assembly
Z1903438biological_processpositive regulation of mitotic cytokinetic process
Z1904781biological_processpositive regulation of protein localization to centrosome
Z1990904cellular_componentribonucleoprotein complex
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: N-acetylalanine => ECO:0007744|PubMed:19413330
ChainResidueDetails
JALA2
VALA2
TSER2
ZSER2
QSER1057
WSER1057

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569
ChainResidueDetails
JSER1523
VSER1523
TSER408
ZSER408
QSER526
WSER526

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163
ChainResidueDetails
JSER1709
USER66
USER430
USER767
VSER1709
TSER418
ZSER418
PSER1165
PSER1167
OSER66
OSER430
OSER767

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:24275569
ChainResidueDetails
JTHR1712
VTHR1712
TTHR373
ZTHR373

site_idSWS_FT_FI5
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163
ChainResidueDetails
JSER1717
VSER1717
TSER468
ZSER468

site_idSWS_FT_FI6
Number of Residues4
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569
ChainResidueDetails
CSER80
ISER80
OSER80
USER80

226707

PDB entries from 2024-10-30

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