5IJG
Crystal structure of O-acetylhomoserine sulfhydrolase from Brucella melitensis at 2.0 A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003962 | molecular_function | cystathionine gamma-synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0009086 | biological_process | methionine biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016846 | molecular_function | carbon-sulfur lyase activity |
| A | 0019346 | biological_process | transsulfuration |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003962 | molecular_function | cystathionine gamma-synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0009086 | biological_process | methionine biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016846 | molecular_function | carbon-sulfur lyase activity |
| B | 0019346 | biological_process | transsulfuration |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue PLP A 501 |
| Chain | Residue |
| A | SER106 |
| A | HOH607 |
| A | HOH628 |
| A | HOH629 |
| A | HOH643 |
| A | GLY107 |
| A | MET108 |
| A | TYR132 |
| A | GLU181 |
| A | ASP216 |
| A | SER238 |
| A | THR240 |
| A | LYS241 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 502 |
| Chain | Residue |
| A | ARG357 |
| B | GLN225 |
| B | LYS226 |
| B | ASP229 |
| B | HIS230 |
| B | GLN336 |
| B | HOH606 |
| B | HOH693 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | binding site for Di-peptide PLP B 501 and LYS B 241 |
| Chain | Residue |
| B | SER106 |
| B | GLY107 |
| B | MET108 |
| B | TYR132 |
| B | GLU181 |
| B | ASP216 |
| B | SER238 |
| B | LEU239 |
| B | THR240 |
| B | TYR242 |
| B | GLY373 |
| B | HOH620 |
| B | HOH630 |
| B | HOH697 |
| B | HOH711 |
Functional Information from PROSITE/UniProt
| site_id | PS00868 |
| Number of Residues | 15 |
| Details | CYS_MET_METAB_PP Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. DLsvySLTKYVgGHS |
| Chain | Residue | Details |
| A | ASP233-SER247 |
