5IIX

Crystal structure of Equine Serum Albumin in the presence of 15 mM zinc at pH 6.5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0005504	molecular_function	fatty acid binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0008289	molecular_function	lipid binding
A	0009267	biological_process	cellular response to starvation
A	0015643	molecular_function	toxic substance binding
A	0019825	molecular_function	oxygen binding
A	0030170	molecular_function	pyridoxal phosphate binding
A	0031667	biological_process	response to nutrient levels
A	0032991	cellular_component	protein-containing complex
A	0046872	molecular_function	metal ion binding
A	0051902	biological_process	negative regulation of mitochondrial depolarization
A	0072732	biological_process	cellular response to calcium ion starvation
A	1903981	molecular_function	enterobactin binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 601

Chain	Residue
A	HIS3
A	GLU6
A	HOH758
A	HOH795

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 602

Chain	Residue
A	HIS67
A	ASP248
A	HOH902
A	HOH953

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN A 603

Chain	Residue
A	HOH789
A	HOH959
A	HOH974
A	HIS18

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN A 604

Chain	Residue
A	HIS145
A	HOH913
A	HOH933
A	HOH956

---

site_id	AC5
Number of Residues	4
Details	binding site for residue ZN A 605

Chain	Residue
A	ASP311
A	HIS317
A	HOH702
A	HOH903

---

site_id	AC6
Number of Residues	4
Details	binding site for residue ZN A 606

Chain	Residue
A	GLU152
A	HIS156
A	HIS287
A	HOH900

---

site_id	AC7
Number of Residues	5
Details	binding site for residue ZN A 607

Chain	Residue
A	ARG435
A	HIS451
A	HOH909
A	HOH943
A	HOH968

---

site_id	AC8
Number of Residues	4
Details	binding site for residue ZN A 608

Chain	Residue
A	GLU517
A	HOH778
A	HOH927
A	HOH938

---

site_id	AC9
Number of Residues	5
Details	binding site for residue ZN A 609

Chain	Residue
A	TYR149
A	HIS241
A	HOH705
A	HOH756
A	HOH934

---

site_id	AD1
Number of Residues	4
Details	binding site for residue ZN A 610

Chain	Residue
A	ASP38
A	ALA78
A	HOH701
A	HOH785

---

site_id	AD2
Number of Residues	2
Details	binding site for residue ZN A 611

Chain	Residue
A	THR507
A	HIS509

---

site_id	AD3
Number of Residues	3
Details	binding site for residue SO4 A 614

Chain	Residue
A	LEU304
A	ALA305
A	ARG336

---

site_id	AD4
Number of Residues	4
Details	binding site for residue SO4 A 615

Chain	Residue
A	LYS499
A	LYS533
A	HOH749
A	HOH881

---

site_id	AD5
Number of Residues	3
Details	binding site for residue SO4 A 616

Chain	Residue
A	ASP163
A	LYS180
A	ARG187

---

site_id	AD6
Number of Residues	4
Details	binding site for residue SO4 A 617

Chain	Residue
A	LYS194
A	ARG217
A	LYS221
A	HOH878

---

site_id	AD7
Number of Residues	6
Details	binding site for residue SO4 A 618

Chain	Residue
A	LYS412
A	THR539
A	LYS540
A	GLU541
A	SO4619
A	HOH848

---

site_id	AD8
Number of Residues	5
Details	binding site for residue SO4 A 619

Chain	Residue
A	ARG409
A	LYS540
A	SO4618
A	HOH842
A	HOH848

---

Functional Information from PROSITE/UniProt

site_id	PS00212
Number of Residues	25
Details	ALBUMIN_1 Albumin domain signature. YkadfteCCpaDdklaCLipkldaL

Chain	Residue	Details
A	TYR160-LEU184
A	TYR352-PHE376
A	PHE550-LEU574

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	192
Details	Domain: {"description":"Albumin 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00769","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	197
Details	Domain: {"description":"Albumin 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00769","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P02770","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P02769","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28567254","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5IIH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	5
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P02768","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	3
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P02768","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Modified residue: {"description":"N6-methyllysine","evidences":[{"source":"UniProtKB","id":"P02768","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P02770","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P07724","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---