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5II0

Crystal structure of the human calcitonin receptor ectodomain in complex with a truncated salmon calcitonin analogue

Functional Information from GO Data
ChainGOidnamespacecontents
A0004930molecular_functionG protein-coupled receptor activity
A0004948molecular_functioncalcitonin receptor activity
A0007186biological_processG protein-coupled receptor signaling pathway
A0016020cellular_componentmembrane
B0004930molecular_functionG protein-coupled receptor activity
B0004948molecular_functioncalcitonin receptor activity
B0007186biological_processG protein-coupled receptor signaling pathway
B0016020cellular_componentmembrane
C0004930molecular_functionG protein-coupled receptor activity
C0004948molecular_functioncalcitonin receptor activity
C0007186biological_processG protein-coupled receptor signaling pathway
C0016020cellular_componentmembrane
D0005179molecular_functionhormone activity
D0005576cellular_componentextracellular region
E0005179molecular_functionhormone activity
E0005576cellular_componentextracellular region
F0005179molecular_functionhormone activity
F0005576cellular_componentextracellular region
Functional Information from PDB Data
site_idAC1
Number of Residues5
Detailsbinding site for residue URE F 101
ChainResidue
CTYR41
CVAL42
CPHE99
FPRO23
FTHR25

Functional Information from PROSITE/UniProt
site_idPS00649
Number of Residues25
DetailsG_PROTEIN_RECEP_F2_1 G-protein coupled receptors family 2 signature 1. CnrtWDgwl.CWddTpagvlsyqfCP
ChainResidueDetails
ACYS72-PRO96

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues12
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN28
CASN73
CASN125
CASN130
AASN73
AASN125
AASN130
BASN28
BASN73
BASN125
BASN130
CASN28

224572

PDB entries from 2024-09-04

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