5IH6

Human Casein Kinase 1 isoform delta (kinase domain) in complex with Epiblastin A derivative

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004672	molecular_function	protein kinase activity
A	0005524	molecular_function	ATP binding
A	0006468	biological_process	protein phosphorylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 301

Chain	Residue
A	HIS50
A	CYS71
A	HIS278
A	SRT302

---

site_id	AC2
Number of Residues	6
Details	binding site for residue SRT A 302

Chain	Residue
A	ZN301
A	HIS50
A	CYS71
A	ARG259
A	HIS278
A	ARG279

---

site_id	AC3
Number of Residues	3
Details	binding site for residue SO4 A 303

Chain	Residue
A	ARG127
A	LYS154
A	LYS171

---

site_id	AC4
Number of Residues	4
Details	binding site for residue SO4 A 304

Chain	Residue
A	ARG178
A	GLN214
A	GLY215
A	LYS224

---

site_id	AC5
Number of Residues	10
Details	binding site for residue AUG A 305

Chain	Residue
A	ILE23
A	ALA36
A	MET80
A	MET82
A	GLU83
A	LEU84
A	LEU85
A	GLY86
A	LEU135
A	ILE148

---

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	24
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGSGSFGDIYlGtdiaagee..........VAIK

Chain	Residue	Details
A	ILE15-LYS38

---

site_id	PS00108
Number of Residues	13
Details	PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. FiHrDVKpdNFLM

Chain	Residue	Details
A	PHE124-MET136

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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