5IG2

Crystal structure of a short chain dehydrogenase/reductase SDR from Burkholderia phymatum in complex with NAD

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0000166	molecular_function	nucleotide binding
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C	0000166	molecular_function	nucleotide binding
C	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Functional Information from PDB Data

site_id	AC1
Number of Residues	33
Details	binding site for residue NAD A 301

Chain	Residue
A	GLY13
A	VAL64
A	ASN90
A	ALA91
A	GLY92
A	VAL93
A	VAL113
A	THR141
A	ALA142
A	SER143
A	TYR156
A	SER16
A	LYS160
A	PRO188
A	ALA189
A	PHE190
A	VAL191
A	THR193
A	GLY194
A	ILE195
A	ARG200
A	VAL201
A	GLY17
A	ACT302
A	HOH468
A	HOH509
A	HOH535
A	PHE18
A	ASP37
A	VAL38
A	ASP39
A	THR62
A	ASP63

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ACT A 302

Chain	Residue
A	SER143
A	TYR156
A	PHE190
A	NAD301

---

site_id	AC3
Number of Residues	33
Details	binding site for residue NAD B 301

Chain	Residue
B	GLY13
B	SER16
B	GLY17
B	PHE18
B	ASP37
B	VAL38
B	ASP39
B	THR62
B	ASP63
B	VAL64
B	ASN90
B	ALA91
B	GLY92
B	VAL93
B	VAL113
B	THR141
B	ALA142
B	SER143
B	TYR156
B	LYS160
B	PRO188
B	ALA189
B	PHE190
B	VAL191
B	THR193
B	GLY194
B	ILE195
B	ARG200
B	VAL201
B	ACT302
B	HOH428
B	HOH437
B	HOH534

---

site_id	AC4
Number of Residues	6
Details	binding site for residue ACT B 302

Chain	Residue
B	SER143
B	TYR156
B	PHE190
B	NAD301
B	HOH513
B	HOH577

---

site_id	AC5
Number of Residues	32
Details	binding site for residue NAD C 301

Chain	Residue
C	GLY194
C	ILE195
C	ARG200
C	VAL201
C	ACT302
C	HOH436
C	HOH454
C	HOH458
C	HOH496
C	GLY13
C	SER16
C	GLY17
C	PHE18
C	ASP37
C	VAL38
C	THR62
C	ASP63
C	VAL64
C	ASN90
C	ALA91
C	GLY92
C	VAL113
C	THR141
C	ALA142
C	SER143
C	TYR156
C	LYS160
C	PRO188
C	ALA189
C	PHE190
C	VAL191
C	THR193

---

site_id	AC6
Number of Residues	4
Details	binding site for residue ACT C 302

Chain	Residue
C	SER143
C	TYR156
C	PHE190
C	NAD301

---