5IFY
Crystal structure of Glucose-1-phosphate thymidylyltransferase from Burkholderia vietnamiensis in complex with 2 -Deoxyuridine-5'-monophosphate and 2'-Deoxy-Thymidine-B-L-Rhamnose
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008879 | molecular_function | glucose-1-phosphate thymidylyltransferase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0008879 | molecular_function | glucose-1-phosphate thymidylyltransferase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0008879 | molecular_function | glucose-1-phosphate thymidylyltransferase activity |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016779 | molecular_function | nucleotidyltransferase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0008879 | molecular_function | glucose-1-phosphate thymidylyltransferase activity |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016779 | molecular_function | nucleotidyltransferase activity |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0008879 | molecular_function | glucose-1-phosphate thymidylyltransferase activity |
| E | 0009058 | biological_process | biosynthetic process |
| E | 0016740 | molecular_function | transferase activity |
| E | 0016779 | molecular_function | nucleotidyltransferase activity |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0008879 | molecular_function | glucose-1-phosphate thymidylyltransferase activity |
| F | 0009058 | biological_process | biosynthetic process |
| F | 0016740 | molecular_function | transferase activity |
| F | 0016779 | molecular_function | nucleotidyltransferase activity |
| F | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | binding site for residue TRH A 500 |
| Chain | Residue |
| A | LEU8 |
| A | TYR145 |
| A | GLY146 |
| A | GLU161 |
| A | LYS162 |
| A | VAL172 |
| A | THR173 |
| A | TYR176 |
| A | ARG194 |
| A | GLU196 |
| A | THR200 |
| A | GLY10 |
| A | HOH612 |
| A | HOH622 |
| A | HOH658 |
| A | HOH672 |
| A | GLY11 |
| A | GLN82 |
| A | PRO85 |
| A | ASP86 |
| A | GLY87 |
| A | LEU88 |
| A | ASP110 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | binding site for residue UMP A 501 |
| Chain | Residue |
| A | TYR114 |
| A | GLY115 |
| A | HIS116 |
| A | ASP117 |
| A | ALA251 |
| A | GLU255 |
| A | ILE256 |
| A | TRP294 |
| A | HOH603 |
| A | HOH609 |
| A | HOH629 |
| A | HOH644 |
| A | HOH669 |
| A | HOH690 |
| B | GLY218 |
| B | ARG219 |
| B | GLY220 |
| site_id | AC3 |
| Number of Residues | 28 |
| Details | binding site for residue TRH B 500 |
| Chain | Residue |
| B | LEU8 |
| B | GLY10 |
| B | GLY11 |
| B | GLN82 |
| B | PRO85 |
| B | ASP86 |
| B | GLY87 |
| B | LEU88 |
| B | LEU108 |
| B | ASP110 |
| B | TYR145 |
| B | GLY146 |
| B | GLU161 |
| B | LYS162 |
| B | VAL172 |
| B | THR173 |
| B | GLY174 |
| B | TYR176 |
| B | ARG194 |
| B | GLU196 |
| B | THR200 |
| B | HOH610 |
| B | HOH614 |
| B | HOH619 |
| B | HOH662 |
| B | HOH667 |
| B | HOH669 |
| B | HOH684 |
| site_id | AC4 |
| Number of Residues | 18 |
| Details | binding site for residue UMP B 501 |
| Chain | Residue |
| A | GLY218 |
| A | ARG219 |
| A | GLY220 |
| B | ILE45 |
| B | TYR114 |
| B | GLY115 |
| B | HIS116 |
| B | ASP117 |
| B | ALA251 |
| B | GLU255 |
| B | ILE256 |
| B | HOH605 |
| B | HOH609 |
| B | HOH646 |
| B | HOH656 |
| B | HOH673 |
| B | HOH705 |
| B | HOH746 |
| site_id | AC5 |
| Number of Residues | 27 |
| Details | binding site for residue TRH C 500 |
| Chain | Residue |
| C | LYS162 |
| C | VAL172 |
| C | THR173 |
| C | TYR176 |
| C | ARG194 |
| C | GLU196 |
| C | THR200 |
| C | HOH610 |
| C | HOH614 |
| C | HOH622 |
| C | HOH635 |
| C | HOH644 |
| C | HOH667 |
| C | HOH677 |
| C | LEU8 |
| C | GLY10 |
| C | GLY11 |
| C | SER12 |
| C | GLN26 |
| C | GLN82 |
| C | PRO85 |
| C | ASP86 |
| C | GLY87 |
| C | ASP110 |
| C | TYR145 |
| C | GLY146 |
| C | GLU161 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | binding site for residue UMP C 501 |
| Chain | Residue |
| C | ILE45 |
| C | TYR114 |
| C | GLY115 |
| C | HIS116 |
| C | ASP117 |
| C | ALA251 |
| C | GLU255 |
| C | ILE256 |
| C | HOH631 |
| C | HOH638 |
| C | HOH654 |
| D | GLY218 |
| D | ARG219 |
| D | GLY220 |
| site_id | AC7 |
| Number of Residues | 20 |
| Details | binding site for residue TRH D 500 |
| Chain | Residue |
| D | LEU8 |
| D | GLY10 |
| D | GLY11 |
| D | GLN82 |
| D | PRO85 |
| D | ASP86 |
| D | GLY87 |
| D | LEU88 |
| D | ASP110 |
| D | TYR145 |
| D | GLY146 |
| D | GLU161 |
| D | LYS162 |
| D | VAL172 |
| D | THR173 |
| D | GLY174 |
| D | TYR176 |
| D | THR200 |
| D | HOH636 |
| D | HOH638 |
| site_id | AC8 |
| Number of Residues | 16 |
| Details | binding site for residue UMP D 501 |
| Chain | Residue |
| C | GLY218 |
| C | ARG219 |
| C | GLY220 |
| D | ILE45 |
| D | TYR114 |
| D | GLY115 |
| D | HIS116 |
| D | ASP117 |
| D | ALA251 |
| D | GLU255 |
| D | ILE256 |
| D | HOH601 |
| D | HOH602 |
| D | HOH609 |
| D | HOH613 |
| D | HOH652 |
| site_id | AC9 |
| Number of Residues | 28 |
| Details | binding site for residue TRH E 500 |
| Chain | Residue |
| E | LEU8 |
| E | GLY10 |
| E | GLY11 |
| E | SER12 |
| E | GLN82 |
| E | PRO85 |
| E | ASP86 |
| E | GLY87 |
| E | LEU88 |
| E | ASP110 |
| E | TYR145 |
| E | GLY146 |
| E | GLU161 |
| E | LYS162 |
| E | VAL172 |
| E | THR173 |
| E | TYR176 |
| E | ARG194 |
| E | GLU196 |
| E | THR200 |
| E | HOH610 |
| E | HOH614 |
| E | HOH622 |
| E | HOH632 |
| E | HOH647 |
| E | HOH660 |
| E | HOH695 |
| E | HOH713 |
| site_id | AD1 |
| Number of Residues | 16 |
| Details | binding site for residue UMP E 501 |
| Chain | Residue |
| E | TYR114 |
| E | GLY115 |
| E | HIS116 |
| E | ASP117 |
| E | GLY218 |
| E | ARG219 |
| E | GLY220 |
| E | VAL250 |
| E | ALA251 |
| E | GLU255 |
| E | ILE256 |
| E | HOH602 |
| E | HOH618 |
| E | HOH644 |
| E | HOH652 |
| E | HOH685 |
| site_id | AD2 |
| Number of Residues | 27 |
| Details | binding site for residue TRH F 500 |
| Chain | Residue |
| F | LEU8 |
| F | GLY10 |
| F | GLY11 |
| F | SER12 |
| F | GLN82 |
| F | PRO85 |
| F | ASP86 |
| F | GLY87 |
| F | LEU88 |
| F | LEU108 |
| F | ASP110 |
| F | TYR145 |
| F | GLY146 |
| F | GLU161 |
| F | LYS162 |
| F | VAL172 |
| F | THR173 |
| F | TYR176 |
| F | ARG194 |
| F | GLU196 |
| F | THR200 |
| F | HOH622 |
| F | HOH643 |
| F | HOH646 |
| F | HOH650 |
| F | HOH674 |
| F | HOH675 |
| site_id | AD3 |
| Number of Residues | 16 |
| Details | binding site for residue UMP F 501 |
| Chain | Residue |
| F | ILE45 |
| F | TYR114 |
| F | GLY115 |
| F | HIS116 |
| F | ASP117 |
| F | GLY218 |
| F | ARG219 |
| F | GLY220 |
| F | ALA251 |
| F | GLU255 |
| F | ILE256 |
| F | HOH601 |
| F | HOH602 |
| F | HOH627 |
| F | HOH641 |
| F | HOH664 |
