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5ID2

Asymmetry in the active site of Mycobacterium tuberculosis AhpE upon exposure to Mycothiol

Functional Information from GO Data
ChainGOidnamespacecontents
A0004601molecular_functionperoxidase activity
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0008379molecular_functionthioredoxin peroxidase activity
A0016209molecular_functionantioxidant activity
A0016491molecular_functionoxidoreductase activity
A0034599biological_processcellular response to oxidative stress
A0045454biological_processcell redox homeostasis
A0051409biological_processresponse to nitrosative stress
A0051920molecular_functionperoxiredoxin activity
A0098869biological_processcellular oxidant detoxification
B0004601molecular_functionperoxidase activity
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0008379molecular_functionthioredoxin peroxidase activity
B0016209molecular_functionantioxidant activity
B0016491molecular_functionoxidoreductase activity
B0034599biological_processcellular response to oxidative stress
B0045454biological_processcell redox homeostasis
B0051409biological_processresponse to nitrosative stress
B0051920molecular_functionperoxiredoxin activity
B0098869biological_processcellular oxidant detoxification
C0004601molecular_functionperoxidase activity
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0008379molecular_functionthioredoxin peroxidase activity
C0016209molecular_functionantioxidant activity
C0016491molecular_functionoxidoreductase activity
C0034599biological_processcellular response to oxidative stress
C0045454biological_processcell redox homeostasis
C0051409biological_processresponse to nitrosative stress
C0051920molecular_functionperoxiredoxin activity
C0098869biological_processcellular oxidant detoxification
D0004601molecular_functionperoxidase activity
D0005515molecular_functionprotein binding
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0008379molecular_functionthioredoxin peroxidase activity
D0016209molecular_functionantioxidant activity
D0016491molecular_functionoxidoreductase activity
D0034599biological_processcellular response to oxidative stress
D0045454biological_processcell redox homeostasis
D0051409biological_processresponse to nitrosative stress
D0051920molecular_functionperoxiredoxin activity
D0098869biological_processcellular oxidant detoxification
Functional Information from PDB Data
site_idAC1
Number of Residues8
Detailsbinding site for residue GOL A 201
ChainResidue
ALEU13
AARG14
ASER92
APHE94
ATRP95
APRO96
AHOH311
AHOH342

site_idAC2
Number of Residues2
Detailsbinding site for residue ACT B 201
ChainResidue
BHOH307
BTHR87

site_idAC3
Number of Residues8
Detailsbinding site for residue GOL B 202
ChainResidue
BASN17
BGLN19
BASN108
BGLN110
BASN115
BGLN134
BHOH322
BHOH348

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: Cysteine sulfenic acid (-SOH) intermediate => ECO:0000269|PubMed:15701515, ECO:0000305|PubMed:19737009, ECO:0007744|PDB:1XVW
ChainResidueDetails
BCYS45
CCYS45

227561

PDB entries from 2024-11-20

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