Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008171 | molecular_function | O-methyltransferase activity |
| A | 0009820 | biological_process | alkaloid metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0017096 | molecular_function | acetylserotonin O-methyltransferase activity |
| A | 0030187 | biological_process | melatonin biosynthetic process |
| A | 0030786 | molecular_function | (RS)-norcoclaurine 6-O-methyltransferase activity |
| A | 0032259 | biological_process | methylation |
| A | 0046983 | molecular_function | protein dimerization activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue SAH A 401 |
| Chain | Residue |
| A | MET166 |
| A | CYS253 |
| A | ILE254 |
| A | ASP257 |
| A | TRP258 |
| A | 2H4402 |
| A | HOH545 |
| A | HOH570 |
| A | HOH605 |
| A | HOH616 |
| A | HOH620 |
| A | THR170 |
| A | HOH629 |
| A | HOH652 |
| A | GLY195 |
| A | ASP218 |
| A | LEU219 |
| A | VAL222 |
| A | ASP238 |
| A | MET239 |
| A | LYS252 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | binding site for residue 2H4 A 402 |
| Chain | Residue |
| A | TRP16 |
| A | TYR20 |
| A | ALA110 |
| A | ILE114 |
| A | ILE148 |
| A | PHE162 |
| A | GLY165 |
| A | MET166 |
| A | ASP169 |
| A | CYS253 |
| A | HIS256 |
| A | ASP257 |
| A | ASP306 |
| A | MET307 |
| A | ASN310 |
| A | SAH401 |
| A | HOH509 |
| A | HOH642 |
| A | HOH740 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue K A 403 |
| Chain | Residue |
| A | HIS124 |
| A | HIS124 |
| A | HOH604 |
| A | HOH604 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue K A 404 |
| Chain | Residue |
| A | ASP289 |
| A | THR297 |
| A | ARG300 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue K A 405 |
| Chain | Residue |
| A | ASN8 |
| A | HIS155 |
| A | PRO156 |
| A | GLU157 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 406 |
| Chain | Residue |
| A | MET3 |
| A | GLU7 |
| A | TRP103 |
| A | ASP104 |
| A | LYS105 |
| A | HOH581 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 407 |
| Chain | Residue |
| A | ASN17 |
| A | ASN17 |
| A | GLY21 |
| A | ASP24 |
| A | ASP24 |
| A | HOH650 |
| A | HOH650 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 408 |
| Chain | Residue |
| A | LYS29 |
| A | LEU112 |
| A | THR115 |
| A | ASP116 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 409 |
| Chain | Residue |
| A | ILE40 |
| A | GLY44 |
| A | GLY91 |
| A | LEU92 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 410 |
| Chain | Residue |
| A | PRO220 |
| A | HIS221 |
| A | HOH503 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS256 | |
| Chain | Residue | Details |
| A | MET166 | |
| A | THR170 | |
| A | GLY195 | |
| A | ASP238 | |
| A | LYS252 | |
| Chain | Residue | Details |
| A | ASP169 | |
| A | CYS253 | |
| A | ASP306 | |
| Chain | Residue | Details |
| A | ASP218 | |
