5IAO

Structure and mapping of spontaneous mutational sites of PyrR from Mycobacterium tuberculosis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004845	molecular_function	uracil phosphoribosyltransferase activity
A	0006351	biological_process	DNA-templated transcription
A	0006355	biological_process	regulation of DNA-templated transcription
A	0009274	cellular_component	peptidoglycan-based cell wall
A	0016740	molecular_function	transferase activity
A	0016757	molecular_function	glycosyltransferase activity
B	0004845	molecular_function	uracil phosphoribosyltransferase activity
B	0006351	biological_process	DNA-templated transcription
B	0006355	biological_process	regulation of DNA-templated transcription
B	0009274	cellular_component	peptidoglycan-based cell wall
B	0016740	molecular_function	transferase activity
B	0016757	molecular_function	glycosyltransferase activity
C	0004845	molecular_function	uracil phosphoribosyltransferase activity
C	0006351	biological_process	DNA-templated transcription
C	0006355	biological_process	regulation of DNA-templated transcription
C	0009274	cellular_component	peptidoglycan-based cell wall
C	0016740	molecular_function	transferase activity
C	0016757	molecular_function	glycosyltransferase activity
D	0004845	molecular_function	uracil phosphoribosyltransferase activity
D	0006351	biological_process	DNA-templated transcription
D	0006355	biological_process	regulation of DNA-templated transcription
D	0009274	cellular_component	peptidoglycan-based cell wall
D	0016740	molecular_function	transferase activity
D	0016757	molecular_function	glycosyltransferase activity
E	0004845	molecular_function	uracil phosphoribosyltransferase activity
E	0006351	biological_process	DNA-templated transcription
E	0006355	biological_process	regulation of DNA-templated transcription
E	0009274	cellular_component	peptidoglycan-based cell wall
E	0016740	molecular_function	transferase activity
E	0016757	molecular_function	glycosyltransferase activity
F	0004845	molecular_function	uracil phosphoribosyltransferase activity
F	0006351	biological_process	DNA-templated transcription
F	0006355	biological_process	regulation of DNA-templated transcription
F	0009274	cellular_component	peptidoglycan-based cell wall
F	0016740	molecular_function	transferase activity
F	0016757	molecular_function	glycosyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue URF A 301

Chain	Residue
A	ARG58
A	HIS177
A	ARG179
A	HOH401

---

site_id	AC2
Number of Residues	4
Details	binding site for residue URF C 301

Chain	Residue
C	ARG58
C	HIS177
C	ARG179
C	HOH403

---

site_id	AC3
Number of Residues	4
Details	binding site for residue URF F 301

Chain	Residue
F	HIS177
F	ARG179
F	HOH423
F	ARG58

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	72
Details	Motif: {"description":"PRPP-binding","evidences":[{"source":"HAMAP-Rule","id":"MF_01219","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	66
Details	Binding site: {"description":"in other chain","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---