5I9N
Crystal structure of B. pseudomallei FabI in complex with NAD and PT412
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 32 |
| Details | binding site for residue NAD A 301 |
| Chain | Residue |
| A | GLY13 |
| A | ILE92 |
| A | GLY93 |
| A | ILE119 |
| A | LEU144 |
| A | SER145 |
| A | TYR146 |
| A | LYS163 |
| A | ALA189 |
| A | GLY190 |
| A | PRO191 |
| A | LEU15 |
| A | ILE192 |
| A | THR194 |
| A | LEU195 |
| A | ALA196 |
| A | 69J302 |
| A | HOH404 |
| A | HOH433 |
| A | HOH443 |
| A | HOH444 |
| A | HOH459 |
| A | SER19 |
| A | HOH469 |
| A | HOH474 |
| A | HOH477 |
| A | ILE20 |
| A | VAL40 |
| A | CYS63 |
| A | ASP64 |
| A | VAL65 |
| A | SER91 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue 69J A 302 |
| Chain | Residue |
| A | GLY93 |
| A | PHE94 |
| A | TYR146 |
| A | TYR156 |
| A | ALA196 |
| A | ALA197 |
| A | PHE203 |
| A | NAD301 |
