5I9L

Crystal structure of B. pseudomallei FabI in complex with NAD and PT404

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004318	molecular_function	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A	0006633	biological_process	fatty acid biosynthetic process
A	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	28
Details	binding site for residue NAD A 301

Chain	Residue
A	GLY13
A	ILE92
A	GLY93
A	LEU144
A	SER145
A	TYR146
A	LYS163
A	ALA189
A	GLY190
A	PRO191
A	ILE192
A	LEU15
A	THR194
A	ALA196
A	9W7302
A	HOH425
A	HOH428
A	HOH454
A	HOH464
A	HOH474
A	HOH507
A	SER19
A	ILE20
A	VAL40
A	CYS63
A	ASP64
A	VAL65
A	SER91

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site_id	AC2
Number of Residues	10
Details	binding site for residue 9W7 A 302

Chain	Residue
A	GLY93
A	PHE94
A	ALA95
A	ILE100
A	TYR146
A	TYR156
A	ALA196
A	ALA197
A	PHE203
A	NAD301

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site_id	AC3
Number of Residues	1
Details	binding site for residue GOL A 303

Chain	Residue
A	ASP235

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