5I9E

Crystal structure of a nuclear actin ternary complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000785	cellular_component	chromatin
A	0000812	cellular_component	Swr1 complex
A	0003682	molecular_function	chromatin binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0006281	biological_process	DNA repair
A	0006325	biological_process	chromatin organization
A	0006338	biological_process	chromatin remodeling
A	0006351	biological_process	DNA-templated transcription
A	0006355	biological_process	regulation of DNA-templated transcription
A	0006357	biological_process	regulation of transcription by RNA polymerase II
A	0016514	cellular_component	SWI/SNF complex
A	0031011	cellular_component	Ino80 complex
A	0035267	cellular_component	NuA4 histone acetyltransferase complex
A	0042393	molecular_function	histone binding
A	0043232	cellular_component	intracellular non-membrane-bounded organelle
A	0051382	biological_process	kinetochore assembly
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005856	cellular_component	cytoskeleton
B	0016787	molecular_function	hydrolase activity
B	0043232	cellular_component	intracellular non-membrane-bounded organelle
C	0000785	cellular_component	chromatin
C	0000812	cellular_component	Swr1 complex
C	0003682	molecular_function	chromatin binding
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005634	cellular_component	nucleus
C	0006281	biological_process	DNA repair
C	0006325	biological_process	chromatin organization
C	0006338	biological_process	chromatin remodeling
C	0006351	biological_process	DNA-templated transcription
C	0006355	biological_process	regulation of DNA-templated transcription
C	0006357	biological_process	regulation of transcription by RNA polymerase II
C	0016514	cellular_component	SWI/SNF complex
C	0031011	cellular_component	Ino80 complex
C	0035267	cellular_component	NuA4 histone acetyltransferase complex
C	0042393	molecular_function	histone binding
C	0043232	cellular_component	intracellular non-membrane-bounded organelle
C	0051382	biological_process	kinetochore assembly
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005856	cellular_component	cytoskeleton
D	0016787	molecular_function	hydrolase activity
D	0043232	cellular_component	intracellular non-membrane-bounded organelle

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue MG A 1001

Chain	Residue
A	ASP159
A	ATP1002

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site_id	AC2
Number of Residues	16
Details	binding site for residue ATP A 1002

Chain	Residue
A	THR164
A	GLN240
A	LYS243
A	GLY412
A	GLY413
A	THR414
A	ILE417
A	GLN449
A	MG1001
A	GLY22
A	SER23
A	TYR24
A	THR25
A	GLY161
A	HIS162
A	ASP163

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site_id	AC3
Number of Residues	2
Details	binding site for residue MG B 401

Chain	Residue
B	ASP11
B	LYS18

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site_id	AC4
Number of Residues	14
Details	binding site for residue ATP C 501

Chain	Residue
C	GLY22
C	SER23
C	TYR24
C	THR25
C	GLY161
C	HIS162
C	ASP163
C	GLN240
C	LYS243
C	GLU244
C	GLY413
C	THR414
C	GLN449
C	MG502

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site_id	AC5
Number of Residues	1
Details	binding site for residue MG C 502

Chain	Residue
C	ATP501

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site_id	AC6
Number of Residues	2
Details	binding site for residue MG D 401

Chain	Residue
D	ASP154
D	VAL339

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Functional Information from PROSITE/UniProt

site_id	PS00406
Number of Residues	11
Details	ACTINS_1 Actins signature 1. YVGDEAQs.KRG

Chain	Residue	Details
B	TYR53-GLY63

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site_id	PS00432
Number of Residues	9
Details	ACTINS_2 Actins signature 2. WISKqEYDE

Chain	Residue	Details
B	TRP356-GLU364

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site_id	PS01132
Number of Residues	13
Details	ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEPvWNSteNR

Chain	Residue	Details
A	LEU109-ARG121
B	LEU104-ARG116

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: N-acetylmethionine => ECO:0000250

Chain	Residue	Details
B	MET1
D	MET1

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