5I93
Structure of Mouse Acireductone dioxygenase with Ni2+ and 2-ketopentanoic acid in the active site
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006555 | biological_process | methionine metabolic process |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009086 | biological_process | methionine biosynthetic process |
| A | 0010308 | molecular_function | acireductone dioxygenase (Ni2+-requiring) activity |
| A | 0010309 | molecular_function | acireductone dioxygenase [iron(II)-requiring] activity |
| A | 0016020 | cellular_component | membrane |
| A | 0016151 | molecular_function | nickel cation binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051213 | molecular_function | dioxygenase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue NI A 201 |
| Chain | Residue |
| A | HIS88 |
| A | HIS90 |
| A | GLU94 |
| A | HIS133 |
| A | HOH307 |
| A | HOH313 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue 69O A 202 |
| Chain | Residue |
| A | ALA145 |
| A | HOH305 |
| A | HOH307 |
| A | HOH313 |
| A | HOH415 |
| A | PHE84 |
| A | ARG96 |
| A | PHE135 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 23 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16783794","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26858196","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1VR3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I8S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I8T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I91","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5I93","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
