5I3I
Structure-Function Studies on Role of Hydrophobic Clamping of a Basic Glutamate in Catalysis by Triosephosphate Isomerase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004807 | molecular_function | triose-phosphate isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006094 | biological_process | gluconeogenesis |
| A | 0006096 | biological_process | glycolytic process |
| A | 0019563 | biological_process | glycerol catabolic process |
| A | 0020015 | cellular_component | glycosome |
| A | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
| B | 0004807 | molecular_function | triose-phosphate isomerase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006094 | biological_process | gluconeogenesis |
| B | 0006096 | biological_process | glycolytic process |
| B | 0019563 | biological_process | glycerol catabolic process |
| B | 0020015 | cellular_component | glycosome |
| B | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
| C | 0004807 | molecular_function | triose-phosphate isomerase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006094 | biological_process | gluconeogenesis |
| C | 0006096 | biological_process | glycolytic process |
| C | 0019563 | biological_process | glycerol catabolic process |
| C | 0020015 | cellular_component | glycosome |
| C | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
| D | 0004807 | molecular_function | triose-phosphate isomerase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006094 | biological_process | gluconeogenesis |
| D | 0006096 | biological_process | glycolytic process |
| D | 0019563 | biological_process | glycerol catabolic process |
| D | 0020015 | cellular_component | glycosome |
| D | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue PGA A 301 |
| Chain | Residue |
| A | ASN11 |
| A | GLY235 |
| A | HOH406 |
| A | HOH418 |
| A | HOH438 |
| A | HOH459 |
| A | LYS13 |
| A | HIS95 |
| A | GLU167 |
| A | ALA171 |
| A | GLY173 |
| A | GLY212 |
| A | SER213 |
| A | GLY234 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue PGA B 301 |
| Chain | Residue |
| B | ASN11 |
| B | LYS13 |
| B | HIS95 |
| B | GLU167 |
| B | ALA171 |
| B | ALA172 |
| B | GLY173 |
| B | GLY212 |
| B | SER213 |
| B | GLY234 |
| B | GLY235 |
| B | HOH406 |
| B | HOH440 |
| B | HOH450 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | binding site for residue PGA C 301 |
| Chain | Residue |
| C | ASN11 |
| C | LYS13 |
| C | HIS95 |
| C | GLU167 |
| C | ALA171 |
| C | GLY173 |
| C | GLY212 |
| C | SER213 |
| C | GLY234 |
| C | GLY235 |
| C | HOH410 |
| C | HOH417 |
| C | HOH438 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | binding site for residue PGA D 301 |
| Chain | Residue |
| D | ASN11 |
| D | LYS13 |
| D | HIS95 |
| D | GLU167 |
| D | ALA171 |
| D | ALA172 |
| D | GLY173 |
| D | GLY212 |
| D | SER213 |
| D | GLY234 |
| D | GLY235 |
| D | HOH401 |
| D | HOH419 |
| D | HOH433 |
| D | HOH447 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Electrophile"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton acceptor"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {} |
| Chain | Residue | Details |
