5I3D
Sulfolobus solfataricus beta-glycosidase - E387Y mutant
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0004565 | molecular_function | beta-galactosidase activity |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0008378 | molecular_function | galactosyltransferase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0004565 | molecular_function | beta-galactosidase activity |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0008378 | molecular_function | galactosyltransferase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| C | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| C | 0004565 | molecular_function | beta-galactosidase activity |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0008378 | molecular_function | galactosyltransferase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| D | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| D | 0004565 | molecular_function | beta-galactosidase activity |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0008378 | molecular_function | galactosyltransferase activity |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue PE8 A 501 |
| Chain | Residue |
| A | GLU112 |
| A | ASN113 |
| A | LYS116 |
| A | ASP119 |
| A | HOH749 |
| A | HOH805 |
| B | ILE413 |
| B | ASN414 |
| B | GLY416 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue ACT A 502 |
| Chain | Residue |
| A | GLU206 |
| A | TRP361 |
| A | ACT503 |
| A | HOH606 |
| A | HOH667 |
| A | HOH732 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 503 |
| Chain | Residue |
| A | PHE359 |
| A | GLU432 |
| A | TRP433 |
| A | ACT502 |
| A | HOH609 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue ACT A 504 |
| Chain | Residue |
| A | TRP84 |
| A | PHE88 |
| A | LEU92 |
| A | LEU118 |
| A | GLU182 |
| A | ARG185 |
| A | PHE186 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue ACT B 501 |
| Chain | Residue |
| B | GLU206 |
| B | TRP361 |
| B | ACT502 |
| B | HOH608 |
| B | HOH640 |
| B | HOH641 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ACT B 502 |
| Chain | Residue |
| B | PHE359 |
| B | GLU432 |
| B | ACT501 |
| B | HOH731 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue ACT B 503 |
| Chain | Residue |
| B | TRP84 |
| B | PHE88 |
| B | LEU92 |
| B | GLU182 |
| B | PHE186 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue ACT B 504 |
| Chain | Residue |
| B | GLU279 |
| B | GLU282 |
| B | TRP287 |
| B | LYS374 |
| B | HOH719 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue ACT C 501 |
| Chain | Residue |
| C | GLU206 |
| C | TRP361 |
| C | ACT502 |
| C | HOH638 |
| C | HOH639 |
| C | HOH651 |
| C | HOH679 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue ACT C 502 |
| Chain | Residue |
| C | PHE359 |
| C | GLU432 |
| C | ACT501 |
| C | HOH612 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue ACT C 503 |
| Chain | Residue |
| C | TRP84 |
| C | PHE88 |
| C | LEU92 |
| C | TRP156 |
| C | GLU182 |
| C | PHE186 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue ACT D 501 |
| Chain | Residue |
| A | ARG463 |
| D | GLU464 |
| D | ASN468 |
| D | ACT502 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue ACT D 502 |
| Chain | Residue |
| A | ARG463 |
| D | GLU474 |
| D | ACT501 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue ACT D 503 |
| Chain | Residue |
| D | GLU206 |
| D | TYR322 |
| D | TRP361 |
| D | ACT504 |
| D | HOH609 |
| D | HOH647 |
| D | HOH726 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue ACT D 504 |
| Chain | Residue |
| D | PHE359 |
| D | GLU432 |
| D | ACT503 |
| D | HOH644 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue ACT D 505 |
| Chain | Residue |
| D | TRP84 |
| D | PHE88 |
| D | LEU92 |
| D | LEU118 |
| D | GLU182 |
| D | PHE186 |
Functional Information from PROSITE/UniProt
| site_id | PS00653 |
| Number of Residues | 15 |
| Details | GLYCOSYL_HYDROL_F1_2 Glycosyl hydrolases family 1 N-terminal signature. FrFGwSqAGFQsEmG |
| Chain | Residue | Details |
| A | PHE8-GLY22 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PROSITE-ProRule","id":"PRU10055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Site: {"description":"Not N6-methylated"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Modified residue: {"description":"N6-methyllysine; partial","evidences":[{"source":"PubMed","id":"14660666","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"N6-methyllysine","evidences":[{"source":"PubMed","id":"14660666","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
