5I2I

Structure of cetuximab Fab with cyclic F3Q variant of the meditope

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue PO4 A 301

Chain	Residue
A	ARG39
A	ARG45
A	PRO59
A	ARG61
A	HOH414

---

site_id	AC2
Number of Residues	6
Details	binding site for residue PO4 B 301

Chain	Residue
B	HOH405
B	HOH410
A	GLU165
A	ASP167
B	HIS170
B	HOH402

---

site_id	AC3
Number of Residues	5
Details	binding site for residue PO4 C 301

Chain	Residue
C	GLU165
C	ASP167
C	HOH413
C	HOH434
D	HIS170

---

site_id	AC4
Number of Residues	5
Details	binding site for residue PO4 C 302

Chain	Residue
C	ARG39
C	ARG45
C	PRO59
C	ARG61
C	HOH409

---

site_id	AC5
Number of Residues	2
Details	binding site for Di-peptide GLY E 1 and GLY E 12

Chain	Residue
E	GLN2
E	LYS11

---

site_id	AC6
Number of Residues	2
Details	binding site for Di-peptide GLY F 1 and GLY F 12

Chain	Residue
F	GLN2
F	LYS11

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
A	TYR192-HIS198
B	TYR200-HIS206

---