5I1W

Crystal structure of CrmK, a flavoenzyme involved in the shunt product recycling mechanism in caerulomycin biosynthesis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0016491	molecular_function	oxidoreductase activity
A	0050660	molecular_function	flavin adenine dinucleotide binding
A	0071949	molecular_function	FAD binding
B	0000166	molecular_function	nucleotide binding
B	0016491	molecular_function	oxidoreductase activity
B	0050660	molecular_function	flavin adenine dinucleotide binding
B	0071949	molecular_function	FAD binding
C	0000166	molecular_function	nucleotide binding
C	0016491	molecular_function	oxidoreductase activity
C	0050660	molecular_function	flavin adenine dinucleotide binding
C	0071949	molecular_function	FAD binding
D	0000166	molecular_function	nucleotide binding
D	0016491	molecular_function	oxidoreductase activity
D	0050660	molecular_function	flavin adenine dinucleotide binding
D	0071949	molecular_function	FAD binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	32
Details	binding site for residue FAD A 601

Chain	Residue
A	ASP23
A	LEU81
A	ALA100
A	GLY122
A	PHE123
A	VAL127
A	GLY128
A	GLY130
A	GLY131
A	HIS132
A	GLY137
A	VAL59
A	TYR138
A	GLY191
A	GLY192
A	GLY195
A	ILE197
A	TYR446
A	ASN448
A	67L602
A	HOH751
A	HOH775
A	ARG60
A	HOH812
A	HOH834
A	HOH845
A	SER61
A	GLY62
A	GLY63
A	HIS64
A	PHE69
A	VAL70

---

site_id	AC2
Number of Residues	7
Details	binding site for residue 67L A 602

Chain	Residue
A	HIS64
A	GLY66
A	PHE403
A	MET405
A	ASN448
A	TYR449
A	FAD601

---

site_id	AC3
Number of Residues	29
Details	binding site for residue FAD B 601

Chain	Residue
B	ASP23
B	VAL59
B	ARG60
B	SER61
B	GLY62
B	GLY63
B	HIS64
B	LEU81
B	ALA100
B	GLY122
B	PHE123
B	VAL127
B	GLY128
B	GLY131
B	HIS132
B	GLY137
B	TYR138
B	GLY191
B	GLY192
B	GLY195
B	ILE197
B	TYR446
B	ASN448
B	67L602
B	HOH762
B	HOH767
B	HOH774
B	HOH799
B	HOH816

---

site_id	AC4
Number of Residues	8
Details	binding site for residue 67L B 602

Chain	Residue
B	HIS64
B	GLY66
B	PHE403
B	MET405
B	TYR449
B	FAD601
B	HOH701
B	HOH811

---

site_id	AC5
Number of Residues	30
Details	binding site for residue FAD C 601

Chain	Residue
C	ASN448
C	67L602
C	HOH725
C	HOH756
C	HOH782
C	HOH832
C	HOH839
C	ASP23
C	VAL59
C	ARG60
C	SER61
C	GLY62
C	GLY63
C	HIS64
C	VAL70
C	LEU81
C	ALA100
C	GLY122
C	PHE123
C	GLY128
C	GLY130
C	GLY131
C	HIS132
C	GLY137
C	TYR138
C	GLY191
C	GLY192
C	GLY195
C	ILE197
C	TYR446

---

site_id	AC6
Number of Residues	6
Details	binding site for residue 67L C 602

Chain	Residue
C	HIS64
C	GLY66
C	PHE403
C	MET405
C	TYR449
C	FAD601

---

site_id	AC7
Number of Residues	31
Details	binding site for residue FAD D 601

Chain	Residue
D	ASP23
D	VAL59
D	ARG60
D	SER61
D	GLY62
D	GLY63
D	HIS64
D	PHE69
D	VAL70
D	LEU81
D	GLY122
D	PHE123
D	VAL127
D	GLY128
D	GLY130
D	GLY131
D	HIS132
D	GLY137
D	TYR138
D	GLY191
D	GLY192
D	GLY195
D	ILE197
D	TYR446
D	ASN448
D	67K602
D	HOH749
D	HOH761
D	HOH764
D	HOH808
D	HOH824

---

site_id	AC8
Number of Residues	6
Details	binding site for residue 67K D 602

Chain	Residue
D	HIS64
D	PHE403
D	MET405
D	TYR449
D	FAD601
D	HOH771

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