5I1K

CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV5-51/IGKV3-20

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue GOL L 301

Chain	Residue
H	PHE172
L	THR179
L	HOH404
H	PRO173
H	VAL175
H	SER183
H	LEU184
H	SER185
L	SER163
L	SER177
L	SER178

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site_id	AC2
Number of Residues	7
Details	binding site for residue GOL L 302

Chain	Residue
H	LEU45
H	TRP47
H	HOH1088
L	LEU97
L	THR98
L	PHE99
L	HOH437

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site_id	AC3
Number of Residues	8
Details	binding site for residue GOL L 303

Chain	Residue
H	ASN161
H	GLN198
H	ILE201
H	NHE901
L	ASP186
L	HOH418
L	HOH445
L	HOH463

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site_id	AC4
Number of Residues	7
Details	binding site for residue SO4 L 304

Chain	Residue
H	LYS19
H	GLN82
L	GLN27
L	SER28
L	HOH457
L	HOH465
L	HOH475

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site_id	AC5
Number of Residues	7
Details	binding site for residue SO4 L 305

Chain	Residue
H	PRO129
H	HOH1013
H	HOH1055
L	SER122
L	ASP123
L	GLU124
L	HOH557

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site_id	AC6
Number of Residues	10
Details	binding site for residue NHE H 901

Chain	Residue
H	LYS74
H	SER162
H	ASN203
H	ASP214
H	HOH1005
H	HOH1115
L	ASP186
L	HIS190
L	GOL303
L	HOH497

---

site_id	AC7
Number of Residues	2
Details	binding site for residue GOL H 902

Chain	Residue
H	ASP100
H	GLY104

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site_id	AC8
Number of Residues	6
Details	binding site for residue SO4 H 903

Chain	Residue
H	TYR27
H	SER28
H	TYR32
H	HOH1068
H	HOH1171
L	ASN153

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site_id	AC9
Number of Residues	6
Details	binding site for residue SO4 H 904

Chain	Residue
H	GLY8
H	ALA9
H	ARG59
H	HOH1147
H	HOH1148
L	SER95

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site_id	AD1
Number of Residues	7
Details	binding site for residue SO4 H 905

Chain	Residue
H	PRO132
H	SER133
H	ALA142
H	ALA143
H	HOH1167
L	PHE117
L	PHE119

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR200-HIS206
L	TYR193-HIS199

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