5I18

CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV1-69/IGKV4-1

Replaces:  3QOT

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue GOL L 901

Chain	Residue
H	HIS170
L	THR170
L	GLU171
L	ASP173
L	SER174
L	GOL903
L	HOH1024
L	HOH1102

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site_id	AC2
Number of Residues	6
Details	binding site for residue GOL L 902

Chain	Residue
L	ARG60
L	SER69
L	GLY70
L	LYS132
L	HOH1029
L	SER58

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site_id	AC3
Number of Residues	8
Details	binding site for residue GOL L 903

Chain	Residue
H	THR166
L	ASP173
L	SER174
L	LYS175
L	GOL901
L	HOH1013
L	HOH1056
L	HOH1167

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site_id	AC4
Number of Residues	11
Details	binding site for residue GOL H 301

Chain	Residue
H	PHE172
H	PRO173
H	VAL175
H	SER183
H	LEU184
H	SER185
H	HOH406
L	SER168
L	SER182
L	SER183
L	THR184

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR200-HIS206
L	TYR198-HIS204

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