Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0031012 | cellular_component | extracellular matrix |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 301 |
| Chain | Residue |
| A | HIS226 |
| A | HIS230 |
| A | HIS236 |
| A | H27306 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 302 |
| Chain | Residue |
| A | HIS175 |
| A | ASP177 |
| A | HIS190 |
| A | HIS203 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 303 |
| Chain | Residue |
| A | GLY183 |
| A | ASP185 |
| A | LEU187 |
| A | ASP205 |
| A | GLU208 |
| A | ASP182 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 304 |
| Chain | Residue |
| A | ASP165 |
| A | GLY197 |
| A | GLN199 |
| A | ASP201 |
| A | HOH420 |
| A | HOH424 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 305 |
| Chain | Residue |
| A | ASP131 |
| A | ASP206 |
| A | GLU208 |
| A | HOH451 |
| A | HOH476 |
| site_id | AC6 |
| Number of Residues | 18 |
| Details | binding site for residue H27 A 306 |
| Chain | Residue |
| A | LEU187 |
| A | LEU188 |
| A | ALA189 |
| A | LYS214 |
| A | LEU222 |
| A | HIS226 |
| A | GLU227 |
| A | HIS230 |
| A | HIS236 |
| A | LEU243 |
| A | TYR245 |
| A | PRO246 |
| A | MET247 |
| A | ASN262 |
| A | HIS266 |
| A | ZN301 |
| A | GOL309 |
| A | HOH404 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 307 |
| Chain | Residue |
| A | ASP113 |
| A | LYS115 |
| A | TRP116 |
| A | HIS117 |
| A | HIS118 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue DMS A 308 |
| Chain | Residue |
| A | TYR179 |
| A | ALA191 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 309 |
| Chain | Residue |
| A | PRO240 |
| A | GLU241 |
| A | ALA242 |
| A | ARG249 |
| A | THR251 |
| A | H27306 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VAAHEFGHAL |
| Chain | Residue | Details |
| A | VAL223-LEU232 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"12051944","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12051944","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12051944","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12077439","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
