Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006212 | biological_process | uracil catabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016812 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047694 | molecular_function | barbiturase activity |
| B | 0006212 | biological_process | uracil catabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016812 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0047694 | molecular_function | barbiturase activity |
| C | 0006212 | biological_process | uracil catabolic process |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016812 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0047694 | molecular_function | barbiturase activity |
| D | 0006212 | biological_process | uracil catabolic process |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016812 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0047694 | molecular_function | barbiturase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 401 |
| Chain | Residue |
| A | ARG34 |
| A | ALA102 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 402 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | binding site for residue MHA A 403 |
| Chain | Residue |
| A | LYS162 |
| A | MET190 |
| A | ASN194 |
| A | SER230 |
| A | SER231 |
| A | LYS328 |
| A | SER347 |
| A | VAL348 |
| A | GLY46 |
| A | GLY47 |
| A | ASP50 |
| A | ARG53 |
| A | SER83 |
| A | GLY84 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 404 |
| Chain | Residue |
| A | GLU301 |
| A | ALA350 |
| A | GLN353 |
| A | GLY354 |
| A | PRO355 |
| A | GLY358 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 401 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 402 |
| Chain | Residue |
| B | GLU301 |
| B | ALA350 |
| B | GLN353 |
| B | GLY354 |
| B | PRO355 |
| B | GLY358 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue NA C 401 |
| Chain | Residue |
| C | GLU301 |
| C | ALA350 |
| C | GLN353 |
| C | GLY354 |
| C | PRO355 |
| C | GLY358 |
| site_id | AC8 |
| Number of Residues | 14 |
| Details | binding site for residue MHA D 402 |
| Chain | Residue |
| D | GLY46 |
| D | ARG53 |
| D | TRP82 |
| D | SER83 |
| D | GLY84 |
| D | LYS162 |
| D | MET190 |
| D | ASN194 |
| D | SER230 |
| D | SER231 |
| D | LYS299 |
| D | LYS328 |
| D | SER347 |
| D | VAL348 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue NA D 403 |
| Chain | Residue |
| D | GLU301 |
| D | ALA350 |
| D | GLN353 |
| D | GLY354 |
| D | PRO355 |
| D | GLY358 |
Functional Information from PROSITE/UniProt
| site_id | PS00136 |
| Number of Residues | 12 |
| Details | SUBTILASE_ASP Serine proteases, subtilase family, aspartic acid active site. AKLIDDGVleaD |
| Chain | Residue | Details |
| A | ALA22-ASP33 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 306 |
| Details | Region: {"description":"RU A","evidences":[{"source":"HAMAP-Rule","id":"MF_01989","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 540 |
| Details | Region: {"description":"RU B","evidences":[{"source":"HAMAP-Rule","id":"MF_01989","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01989","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"HAMAP-Rule","id":"MF_01989","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 48 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01989","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"28235873","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Site: {"description":"Important for substrate specificity","evidences":[{"source":"HAMAP-Rule","id":"MF_01989","evidenceCode":"ECO:0000255"}]} |
