5HWP

MvaS with acetylated Cys115 in complex with coenzyme A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004421	molecular_function	hydroxymethylglutaryl-CoA synthase activity
A	0006084	biological_process	acetyl-CoA metabolic process
A	0010142	biological_process	farnesyl diphosphate biosynthetic process, mevalonate pathway
A	0016746	molecular_function	acyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue SO4 A 501

Chain	Residue
A	ARG246
A	GLN333

---

site_id	AC2
Number of Residues	6
Details	binding site for residue GOL A 502

Chain	Residue
A	LYS101
A	LYS101
A	LEU102
A	LEU102
A	HOH705
A	HOH749

---

site_id	AC3
Number of Residues	24
Details	binding site for residue COA A 503

Chain	Residue
A	ASP31
A	ALA33
A	LYS34
A	GLY38
A	TYR149
A	ALA154
A	GLY155
A	THR158
A	GLY205
A	HIS206
A	SER208
A	PRO252
A	PHE253
A	LYS259
A	HOH604
A	HOH639
A	HOH647
A	HOH665
A	HOH673
A	HOH709
A	HOH741
A	HOH753
A	HOH771
A	ASP31

---