5HWP
MvaS with acetylated Cys115 in complex with coenzyme A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004421 | molecular_function | hydroxymethylglutaryl-CoA synthase activity |
| A | 0006084 | biological_process | acetyl-CoA metabolic process |
| A | 0010142 | biological_process | farnesyl diphosphate biosynthetic process, mevalonate pathway |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 501 |
| Chain | Residue |
| A | ARG246 |
| A | GLN333 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 502 |
| Chain | Residue |
| A | LYS101 |
| A | LYS101 |
| A | LEU102 |
| A | LEU102 |
| A | HOH705 |
| A | HOH749 |
| site_id | AC3 |
| Number of Residues | 24 |
| Details | binding site for residue COA A 503 |
| Chain | Residue |
| A | ASP31 |
| A | ALA33 |
| A | LYS34 |
| A | GLY38 |
| A | TYR149 |
| A | ALA154 |
| A | GLY155 |
| A | THR158 |
| A | GLY205 |
| A | HIS206 |
| A | SER208 |
| A | PRO252 |
| A | PHE253 |
| A | LYS259 |
| A | HOH604 |
| A | HOH639 |
| A | HOH647 |
| A | HOH665 |
| A | HOH673 |
| A | HOH709 |
| A | HOH741 |
| A | HOH753 |
| A | HOH771 |
| A | ASP31 |
