5HWN
Crystal structure of keto-deoxy-D-galactarate dehydratase complexed with pyruvate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008840 | molecular_function | 4-hydroxy-tetrahydrodipicolinate synthase activity |
| A | 0016052 | biological_process | carbohydrate catabolic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019394 | biological_process | glucarate catabolic process |
| A | 0042838 | biological_process | D-glucarate catabolic process |
| A | 0047448 | molecular_function | 5-dehydro-4-deoxyglucarate dehydratase activity |
| B | 0008840 | molecular_function | 4-hydroxy-tetrahydrodipicolinate synthase activity |
| B | 0016052 | biological_process | carbohydrate catabolic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0019394 | biological_process | glucarate catabolic process |
| B | 0042838 | biological_process | D-glucarate catabolic process |
| B | 0047448 | molecular_function | 5-dehydro-4-deoxyglucarate dehydratase activity |
| C | 0008840 | molecular_function | 4-hydroxy-tetrahydrodipicolinate synthase activity |
| C | 0016052 | biological_process | carbohydrate catabolic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0019394 | biological_process | glucarate catabolic process |
| C | 0042838 | biological_process | D-glucarate catabolic process |
| C | 0047448 | molecular_function | 5-dehydro-4-deoxyglucarate dehydratase activity |
| D | 0008840 | molecular_function | 4-hydroxy-tetrahydrodipicolinate synthase activity |
| D | 0016052 | biological_process | carbohydrate catabolic process |
| D | 0016829 | molecular_function | lyase activity |
| D | 0019394 | biological_process | glucarate catabolic process |
| D | 0042838 | biological_process | D-glucarate catabolic process |
| D | 0047448 | molecular_function | 5-dehydro-4-deoxyglucarate dehydratase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue PYR A 401 |
| Chain | Residue |
| A | PHE17 |
| A | GLY53 |
| A | THR54 |
| A | TYR140 |
| A | LYS166 |
| A | SER211 |
| A | HOH516 |
| A | HOH549 |
| A | HOH630 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | MET187 |
| A | TYR188 |
| A | GLY206 |
| A | THR208 |
| A | THR209 |
| A | GOL407 |
| A | HOH576 |
| A | HOH592 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 403 |
| Chain | Residue |
| A | GLY13 |
| A | LEU14 |
| A | PRO46 |
| A | HOH540 |
| A | HOH635 |
| A | HOH697 |
| B | ALA303 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue GOL A 404 |
| Chain | Residue |
| A | ARG234 |
| A | GLU238 |
| A | HOH502 |
| A | HOH512 |
| A | HOH518 |
| A | HOH524 |
| A | HOH596 |
| A | HOH606 |
| D | THR179 |
| D | GLY183 |
| D | ASP184 |
| D | GLY206 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 405 |
| Chain | Residue |
| A | TYR43 |
| A | PRO219 |
| A | GLY220 |
| A | LEU221 |
| A | HIS299 |
| A | HOH624 |
| B | THR298 |
| B | HIS299 |
| B | LYS300 |
| B | GOL402 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue FMT A 406 |
| Chain | Residue |
| A | GLY53 |
| A | ARG142 |
| A | HOH508 |
| A | HOH549 |
| A | HOH554 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 407 |
| Chain | Residue |
| A | GLY11 |
| A | ARG230 |
| A | GOL402 |
| A | HOH557 |
| A | HOH614 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 402 |
| Chain | Residue |
| A | THR298 |
| A | GOL405 |
| B | TYR43 |
| B | PRO219 |
| B | GLY220 |
| B | LEU221 |
| B | HIS299 |
| B | HOH665 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 403 |
| Chain | Residue |
| B | MET187 |
| B | TYR188 |
| B | GLY206 |
| B | PHE207 |
| B | THR208 |
| B | THR209 |
| B | HOH621 |
| B | HOH657 |
| B | HOH757 |
| site_id | AD1 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 404 |
| Chain | Residue |
| B | ARG234 |
| B | GLU238 |
| B | HOH501 |
| B | HOH504 |
| B | HOH519 |
| C | THR179 |
| C | GLY183 |
| C | GLY206 |
| C | HOH580 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue FMT B 405 |
| Chain | Residue |
| B | GLY53 |
| B | ARG142 |
| B | HOH641 |
| site_id | AD3 |
| Number of Residues | 8 |
| Details | binding site for residue GOL C 402 |
| Chain | Residue |
| C | MET187 |
| C | TYR188 |
| C | GLY206 |
| C | PHE207 |
| C | THR208 |
| C | THR209 |
| C | HOH566 |
| C | HOH618 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue FMT C 403 |
| Chain | Residue |
| C | GLY53 |
| C | ARG142 |
| C | HOH523 |
| site_id | AD5 |
| Number of Residues | 8 |
| Details | binding site for residue GOL D 402 |
| Chain | Residue |
| A | HOH603 |
| D | ARG234 |
| D | GLU238 |
| D | HOH502 |
| D | HOH656 |
| A | THR179 |
| A | GLY183 |
| A | GLY206 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue GOL D 403 |
| Chain | Residue |
| D | GLY11 |
| D | ARG230 |
| D | GOL404 |
| D | HOH506 |
| D | HOH517 |
| D | HOH524 |
| site_id | AD7 |
| Number of Residues | 8 |
| Details | binding site for residue GOL D 404 |
| Chain | Residue |
| D | MET187 |
| D | TYR188 |
| D | PHE207 |
| D | THR208 |
| D | THR209 |
| D | GOL403 |
| D | HOH560 |
| D | HOH608 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue FMT D 405 |
| Chain | Residue |
| D | GLY53 |
| D | PHE58 |
| D | ARG142 |
| D | HOH530 |
| site_id | AD9 |
| Number of Residues | 14 |
| Details | binding site for Di-peptide PYR B 401 and LYS B 166 |
| Chain | Residue |
| B | PHE17 |
| B | GLY53 |
| B | THR54 |
| B | VAL139 |
| B | TYR140 |
| B | ASN141 |
| B | PHE165 |
| B | ASP167 |
| B | LEU189 |
| B | GLY190 |
| B | GLY191 |
| B | SER211 |
| B | HOH524 |
| B | HOH728 |
| site_id | AE1 |
| Number of Residues | 14 |
| Details | binding site for Di-peptide PYR C 401 and LYS C 166 |
| Chain | Residue |
| C | PHE17 |
| C | GLY53 |
| C | THR54 |
| C | VAL139 |
| C | TYR140 |
| C | ASN141 |
| C | PHE165 |
| C | ASP167 |
| C | LEU189 |
| C | GLY190 |
| C | GLY191 |
| C | SER211 |
| C | HOH516 |
| C | HOH612 |
| site_id | AE2 |
| Number of Residues | 15 |
| Details | binding site for Di-peptide PYR D 401 and LYS D 166 |
| Chain | Residue |
| D | PHE17 |
| D | GLY53 |
| D | THR54 |
| D | VAL139 |
| D | TYR140 |
| D | ASN141 |
| D | PHE165 |
| D | ASP167 |
| D | LEU189 |
| D | GLY190 |
| D | GLY191 |
| D | SER211 |
| D | HOH501 |
| D | HOH516 |
| D | HOH607 |
