5HWM
Crystal structure of keto-deoxy-D-galactarate dehydratase complexed with 2-oxoadipic acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008840 | molecular_function | 4-hydroxy-tetrahydrodipicolinate synthase activity |
| A | 0016052 | biological_process | carbohydrate catabolic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0042838 | biological_process | D-glucarate catabolic process |
| A | 0047448 | molecular_function | 5-dehydro-4-deoxyglucarate dehydratase activity |
| B | 0008840 | molecular_function | 4-hydroxy-tetrahydrodipicolinate synthase activity |
| B | 0016052 | biological_process | carbohydrate catabolic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0042838 | biological_process | D-glucarate catabolic process |
| B | 0047448 | molecular_function | 5-dehydro-4-deoxyglucarate dehydratase activity |
| C | 0008840 | molecular_function | 4-hydroxy-tetrahydrodipicolinate synthase activity |
| C | 0016052 | biological_process | carbohydrate catabolic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0042838 | biological_process | D-glucarate catabolic process |
| C | 0047448 | molecular_function | 5-dehydro-4-deoxyglucarate dehydratase activity |
| D | 0008840 | molecular_function | 4-hydroxy-tetrahydrodipicolinate synthase activity |
| D | 0016052 | biological_process | carbohydrate catabolic process |
| D | 0016829 | molecular_function | lyase activity |
| D | 0042838 | biological_process | D-glucarate catabolic process |
| D | 0047448 | molecular_function | 5-dehydro-4-deoxyglucarate dehydratase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue OOG A 401 |
| Chain | Residue |
| A | PHE17 |
| A | THR194 |
| A | SER211 |
| A | ALA213 |
| A | ALA259 |
| A | HOH534 |
| A | HOH632 |
| A | GLY53 |
| A | THR54 |
| A | LEU108 |
| A | TYR140 |
| A | LYS166 |
| A | GLY191 |
| A | MET192 |
| A | PRO193 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue FMT C 402 |
| Chain | Residue |
| C | GLY53 |
| C | PHE58 |
| C | ARG142 |
| C | VAL260 |
| D | ILE115 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue FMT D 402 |
| Chain | Residue |
| D | ARG142 |
| site_id | AC4 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide OOG B 401 and LYS B 166 |
| Chain | Residue |
| B | PHE17 |
| B | GLY53 |
| B | THR54 |
| B | VAL139 |
| B | TYR140 |
| B | ASN141 |
| B | PHE165 |
| B | ASP167 |
| B | LEU189 |
| B | GLY191 |
| B | MET192 |
| B | PRO193 |
| B | THR194 |
| B | SER211 |
| B | ALA213 |
| B | ALA259 |
| B | HOH504 |
| B | HOH509 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide OOG B 401 and LYS B 166 |
| Chain | Residue |
| B | PHE17 |
| B | GLY53 |
| B | THR54 |
| B | VAL139 |
| B | TYR140 |
| B | ASN141 |
| B | PHE165 |
| B | ASP167 |
| B | LEU189 |
| B | GLY191 |
| B | MET192 |
| B | PRO193 |
| B | THR194 |
| B | SER211 |
| B | ALA213 |
| B | ALA259 |
| B | HOH504 |
| B | HOH509 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | binding site for Di-peptide OOG C 401 and LYS C 166 |
| Chain | Residue |
| C | PHE17 |
| C | GLY53 |
| C | THR54 |
| C | VAL139 |
| C | TYR140 |
| C | ASN141 |
| C | PHE165 |
| C | ASP167 |
| C | LEU189 |
| C | GLY191 |
| C | SER211 |
| C | SER212 |
| C | ALA213 |
| C | HOH563 |
| site_id | AC7 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide OOG D 401 and LYS D 166 |
| Chain | Residue |
| D | PHE17 |
| D | GLY53 |
| D | THR54 |
| D | LEU108 |
| D | VAL139 |
| D | TYR140 |
| D | ASN141 |
| D | PHE165 |
| D | ASP167 |
| D | LEU189 |
| D | GLY191 |
| D | MET192 |
| D | PRO193 |
| D | THR194 |
| D | ALA195 |
| D | SER211 |
| D | ALA213 |
| D | HOH512 |
