5HVN
3.0 Angstrom Crystal Structure of 3-dehydroquinate Synthase (AroB) from Francisella tularensis in Complex with NAD.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003856 | molecular_function | 3-dehydroquinate synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016838 | molecular_function | carbon-oxygen lyase activity, acting on phosphates |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | binding site for residue NAD A 401 |
| Chain | Residue |
| A | ASN42 |
| A | VAL106 |
| A | ASP109 |
| A | THR129 |
| A | THR130 |
| A | LEU132 |
| A | ASP136 |
| A | SER137 |
| A | LYS142 |
| A | ASN152 |
| A | PHE169 |
| A | THR44 |
| A | THR172 |
| A | LEU173 |
| A | GLU177 |
| A | HOH507 |
| A | HOH508 |
| A | LEU48 |
| A | TYR49 |
| A | ASP70 |
| A | GLU72 |
| A | LYS75 |
| A | GLY104 |
| A | GLY105 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 402 |
| Chain | Residue |
| A | GLY246 |
| A | THR248 |
| A | ILE333 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JAN-2016","submissionDatabase":"PDB data bank","title":"3.0 angstrom crystal structure of 3-dehydroquinate synthase (AroB) from Francisella tularensis in complex with NAD.","authors":["Minasov G.","Light S.H.","Shuvalova L.","Dubrovska I.","Winsor J.","Zhou M.","Grimshaw S.","Kwon K.","Joachimiak A.","Anderson W.F."]}},{"source":"PDB","id":"5HVN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00110","evidenceCode":"ECO:0000255"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JAN-2016","submissionDatabase":"PDB data bank","title":"3.0 angstrom crystal structure of 3-dehydroquinate synthase (AroB) from Francisella tularensis in complex with NAD.","authors":["Minasov G.","Light S.H.","Shuvalova L.","Dubrovska I.","Winsor J.","Zhou M.","Grimshaw S.","Kwon K.","Joachimiak A.","Anderson W.F."]}},{"source":"PDB","id":"5HVN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00110","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
