5HVN

3.0 Angstrom Crystal Structure of 3-dehydroquinate Synthase (AroB) from Francisella tularensis in Complex with NAD.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003856	molecular_function	3-dehydroquinate synthase activity
A	0005737	cellular_component	cytoplasm
A	0008652	biological_process	amino acid biosynthetic process
A	0009073	biological_process	aromatic amino acid family biosynthetic process
A	0009423	biological_process	chorismate biosynthetic process
A	0016829	molecular_function	lyase activity
A	0016838	molecular_function	carbon-oxygen lyase activity, acting on phosphates
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	24
Details	binding site for residue NAD A 401

Chain	Residue
A	ASN42
A	VAL106
A	ASP109
A	THR129
A	THR130
A	LEU132
A	ASP136
A	SER137
A	LYS142
A	ASN152
A	PHE169
A	THR44
A	THR172
A	LEU173
A	GLU177
A	HOH507
A	HOH508
A	LEU48
A	TYR49
A	ASP70
A	GLU72
A	LYS75
A	GLY104
A	GLY105

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site_id	AC2
Number of Residues	3
Details	binding site for residue CL A 402

Chain	Residue
A	GLY246
A	THR248
A	ILE333

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|Ref.2, ECO:0007744|PDB:5HVN

Chain	Residue	Details
A	ASN42

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site_id	SWS_FT_FI2
Number of Residues	5
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00110, ECO:0000269|Ref.2, ECO:0007744|PDB:5HVN

Chain	Residue	Details
A	ASP70
A	GLY105
A	THR129
A	LYS142
A	PHE169

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site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00110

Chain	Residue	Details
A	LYS151
A	GLU184
A	HIS247
A	HIS264

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