Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5HUO

Crystal Structure of NadC Deletion Mutant in C2221 Space Group

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004514	molecular_function	nicotinate-nucleotide diphosphorylase (carboxylating) activity
A	0005737	cellular_component	cytoplasm
A	0009435	biological_process	NAD+ biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016757	molecular_function	glycosyltransferase activity
A	0016763	molecular_function	pentosyltransferase activity
A	0019363	biological_process	pyridine nucleotide biosynthetic process
A	0034213	biological_process	quinolinate catabolic process
B	0004514	molecular_function	nicotinate-nucleotide diphosphorylase (carboxylating) activity
B	0005737	cellular_component	cytoplasm
B	0009435	biological_process	NAD+ biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016757	molecular_function	glycosyltransferase activity
B	0016763	molecular_function	pentosyltransferase activity
B	0019363	biological_process	pyridine nucleotide biosynthetic process
B	0034213	biological_process	quinolinate catabolic process
C	0004514	molecular_function	nicotinate-nucleotide diphosphorylase (carboxylating) activity
C	0005737	cellular_component	cytoplasm
C	0009435	biological_process	NAD+ biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016757	molecular_function	glycosyltransferase activity
C	0016763	molecular_function	pentosyltransferase activity
C	0019363	biological_process	pyridine nucleotide biosynthetic process
C	0034213	biological_process	quinolinate catabolic process
E	0004514	molecular_function	nicotinate-nucleotide diphosphorylase (carboxylating) activity
E	0005737	cellular_component	cytoplasm
E	0009435	biological_process	NAD+ biosynthetic process
E	0016740	molecular_function	transferase activity
E	0016757	molecular_function	glycosyltransferase activity
E	0016763	molecular_function	pentosyltransferase activity
E	0019363	biological_process	pyridine nucleotide biosynthetic process
E	0034213	biological_process	quinolinate catabolic process
F	0004514	molecular_function	nicotinate-nucleotide diphosphorylase (carboxylating) activity
F	0005737	cellular_component	cytoplasm
F	0009435	biological_process	NAD+ biosynthetic process
F	0016740	molecular_function	transferase activity
F	0016757	molecular_function	glycosyltransferase activity
F	0016763	molecular_function	pentosyltransferase activity
F	0019363	biological_process	pyridine nucleotide biosynthetic process
F	0034213	biological_process	quinolinate catabolic process
H	0004514	molecular_function	nicotinate-nucleotide diphosphorylase (carboxylating) activity
H	0005737	cellular_component	cytoplasm
H	0009435	biological_process	NAD+ biosynthetic process
H	0016740	molecular_function	transferase activity
H	0016757	molecular_function	glycosyltransferase activity
H	0016763	molecular_function	pentosyltransferase activity
H	0019363	biological_process	pyridine nucleotide biosynthetic process
H	0034213	biological_process	quinolinate catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue SO4 A 301

Chain	Residue
A	ARG242
E	ARG190

site_id	AC2
Number of Residues	3
Details	binding site for residue SO4 A 302

Chain	Residue
A	ARG242
E	ARG190
E	PHE195

site_id	AC3
Number of Residues	4
Details	binding site for residue SO4 A 303

Chain	Residue
A	LYS140
A	SER267
A	GLY268
A	HIS272

site_id	AC4
Number of Residues	4
Details	binding site for residue SO4 A 304

Chain	Residue
A	ARG139
A	ARG162
A	MET170
A	LYS172

site_id	AC5
Number of Residues	4
Details	binding site for residue SO4 B 301

Chain	Residue
B	ARG139
B	ARG162
B	MET170
B	LYS172

site_id	AC6
Number of Residues	4
Details	binding site for residue SO4 B 302

Chain	Residue
B	LYS140
B	GLY268
B	SER269
B	HIS272

site_id	AC7
Number of Residues	2
Details	binding site for residue SO4 B 303

Chain	Residue
B	LYS140
H	ARG105

site_id	AC8
Number of Residues	3
Details	binding site for residue SO4 C 301

Chain	Residue
C	LYS49
C	SER280
C	LYS282

site_id	AC9
Number of Residues	2
Details	binding site for residue SO4 C 302

Chain	Residue
C	LYS140
C	GLY268

site_id	AD1
Number of Residues	1
Details	binding site for residue SO4 E 301

Chain	Residue
E	ARG242

site_id	AD2
Number of Residues	5
Details	binding site for residue SO4 E 302

Chain	Residue
C	ARG105
E	LYS140
E	LYS172
E	GLU202
E	HOH402

site_id	AD3
Number of Residues	6
Details	binding site for residue SO4 E 303

Chain	Residue
E	ARG139
E	ARG162
E	MET170
E	LYS172
E	HOH401
E	HOH406

site_id	AD4
Number of Residues	3
Details	binding site for residue SO4 E 304

Chain	Residue
E	LYS140
E	GLY268
E	HIS272

site_id	AD5
Number of Residues	3
Details	binding site for residue SO4 F 301

Chain	Residue
F	ARG139
F	ARG162
F	LYS172

site_id	AD6
Number of Residues	5
Details	binding site for residue SO4 F 302

Chain	Residue
F	LYS140
F	SER267
F	GLY268
F	SER269
F	HIS272

site_id	AD7
Number of Residues	2
Details	binding site for residue SO4 F 303

Chain	Residue
F	ARG62
H	SO4303

site_id	AD8
Number of Residues	4
Details	binding site for residue SO4 H 301

Chain	Residue
H	ARG139
H	ARG162
H	MET170
H	LYS172

site_id	AD9
Number of Residues	3
Details	binding site for residue SO4 H 302

Chain	Residue
H	LYS140
H	GLY268
H	HIS272

site_id	AE1
Number of Residues	3
Details	binding site for residue SO4 H 303

Chain	Residue
F	SO4303
H	ARG62
H	THR65

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)