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5HU3

Drosophila CaMKII-D136N in complex with a phosphorylated fragment of the Eag potassium channel and Mg2+/ADP

Functional Information from GO Data
ChainGOidnamespacecontents
A0004672molecular_functionprotein kinase activity
A0005524molecular_functionATP binding
A0006468biological_processprotein phosphorylation
Functional Information from PDB Data
site_idAC1
Number of Residues22
Detailsbinding site for residue ADP A 301
ChainResidue
AGLY21
AGLU97
AGLU140
AASN141
ALEU143
AASP157
AMG302
AHOH407
AHOH424
AHOH427
AHOH432
AGLY23
AHOH457
BARG784
BTPO787
AALA24
ASER26
AVAL28
AALA41
ALYS43
AASP91
AVAL93

site_idAC2
Number of Residues5
Detailsbinding site for residue MG A 302
ChainResidue
AASN141
AASP157
AADP301
AHOH457
BTPO787

Functional Information from PROSITE/UniProt
site_idPS00107
Number of Residues24
DetailsPROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGKGAFSIVKrCvqkstgfe..........FAAK
ChainResidueDetails
ALEU20-LYS43

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphothreonine; by CaMK2 => ECO:0000269|PubMed:11980904
ChainResidueDetails
BTPO787

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00159
ChainResidueDetails
ALEU20
ALYS43

227111

PDB entries from 2024-11-06

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