Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0016020 | cellular_component | membrane |
B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
B | 0006508 | biological_process | proteolysis |
B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 16 |
Details | binding site for residue 66F A 501 |
Chain | Residue |
A | SER71 |
A | TRP176 |
A | ASP289 |
A | SER290 |
A | GLY291 |
A | THR292 |
A | THR293 |
A | ALA396 |
A | GLN73 |
A | GLY74 |
A | LEU91 |
A | ASP93 |
A | TYR132 |
A | GLN134 |
A | PHE169 |
A | ILE171 |
site_id | AC2 |
Number of Residues | 18 |
Details | binding site for residue 66F B 501 |
Chain | Residue |
B | SER71 |
B | GLN73 |
B | GLY74 |
B | LEU91 |
B | ASP93 |
B | TYR132 |
B | GLN134 |
B | PHE169 |
B | ILE171 |
B | TRP176 |
B | ILE179 |
B | ASP289 |
B | SER290 |
B | GLY291 |
B | THR292 |
B | THR293 |
B | ALA396 |
B | HOH927 |
Functional Information from PROSITE/UniProt
site_id | PS00141 |
Number of Residues | 12 |
Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
Chain | Residue | Details |
A | ILE90-VAL101 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP93 | |
A | ASP289 | |
B | ASP93 | |
B | ASP289 | |
Chain | Residue | Details |
A | LYS126 | |
B | LYS279 | |
B | LYS285 | |
B | LYS299 | |
B | LYS300 | |
B | LYS307 | |
A | LYS275 | |
A | LYS279 | |
A | LYS285 | |
A | LYS299 | |
A | LYS300 | |
A | LYS307 | |
B | LYS126 | |
B | LYS275 | |
site_id | SWS_FT_FI3 |
Number of Residues | 8 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
Chain | Residue | Details |
A | ASN153 | |
A | ASN172 | |
A | ASN223 | |
A | ASN354 | |
B | ASN153 | |
B | ASN172 | |
B | ASN223 | |
B | ASN354 | |