5HSS

Linalool dehydratase/isomerase: Ldi with monoterpene substrate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016098	biological_process	monoterpenoid metabolic process
A	0016829	molecular_function	lyase activity
A	0016836	molecular_function	hydro-lyase activity
A	0016853	molecular_function	isomerase activity
A	0042597	cellular_component	periplasmic space
A	0043694	biological_process	monoterpene catabolic process
A	0050486	molecular_function	intramolecular hydroxytransferase activity
B	0016098	biological_process	monoterpenoid metabolic process
B	0016829	molecular_function	lyase activity
B	0016836	molecular_function	hydro-lyase activity
B	0016853	molecular_function	isomerase activity
B	0042597	cellular_component	periplasmic space
B	0043694	biological_process	monoterpene catabolic process
B	0050486	molecular_function	intramolecular hydroxytransferase activity
C	0016098	biological_process	monoterpenoid metabolic process
C	0016829	molecular_function	lyase activity
C	0016836	molecular_function	hydro-lyase activity
C	0016853	molecular_function	isomerase activity
C	0042597	cellular_component	periplasmic space
C	0043694	biological_process	monoterpene catabolic process
C	0050486	molecular_function	intramolecular hydroxytransferase activity
D	0016098	biological_process	monoterpenoid metabolic process
D	0016829	molecular_function	lyase activity
D	0016836	molecular_function	hydro-lyase activity
D	0016853	molecular_function	isomerase activity
D	0042597	cellular_component	periplasmic space
D	0043694	biological_process	monoterpene catabolic process
D	0050486	molecular_function	intramolecular hydroxytransferase activity
E	0016098	biological_process	monoterpenoid metabolic process
E	0016829	molecular_function	lyase activity
E	0016836	molecular_function	hydro-lyase activity
E	0016853	molecular_function	isomerase activity
E	0042597	cellular_component	periplasmic space
E	0043694	biological_process	monoterpene catabolic process
E	0050486	molecular_function	intramolecular hydroxytransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue PG0 A 401

Chain	Residue
A	LEU340
B	ILE40

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site_id	AC2
Number of Residues	10
Details	binding site for residue 64Z A 402

Chain	Residue
B	ASP38
B	PHE39
B	TYR44
A	MET124
A	CYS170
A	PHE176
A	CYS179
A	TYR239
A	LEU294
A	LEU341

---

site_id	AC3
Number of Residues	2
Details	binding site for residue PG0 B 401

Chain	Residue
B	LEU340
E	PHE39

---

site_id	AC4
Number of Residues	6
Details	binding site for residue 650 B 402

Chain	Residue
B	TYR65
B	PHE176
B	CYS179
B	LEU294
E	PHE39
E	TYR44

---

site_id	AC5
Number of Residues	9
Details	binding site for residue 650 C 401

Chain	Residue
C	TYR65
C	MET124
C	CYS170
C	PHE176
C	CYS179
C	TYR239
C	LEU294
D	PHE39
D	TYR44

---

site_id	AC6
Number of Residues	1
Details	binding site for residue PG0 D 401

Chain	Residue
D	PHE39

---

site_id	AC7
Number of Residues	2
Details	binding site for residue PG0 D 402

Chain	Residue
A	PHE39
D	LEU340

---

site_id	AC8
Number of Residues	10
Details	binding site for residue 64Z D 403

Chain	Residue
A	ASP38
A	PHE39
A	TYR44
D	MET124
D	CYS170
D	PHE176
D	CYS179
D	TYR239
D	LEU294
D	LEU341

---

site_id	AC9
Number of Residues	1
Details	binding site for residue PG0 E 401

Chain	Residue
E	PRO59

---

site_id	AD1
Number of Residues	10
Details	binding site for residue 64Z E 402

Chain	Residue
C	ASP38
C	PHE39
C	TYR44
E	TYR65
E	MET124
E	CYS170
E	PHE176
E	CYS179
E	TYR239
E	LEU341

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"Reference","evidenceCode":"ECO:0000305","citation":{"citationType":"journal article","publicationDate":"2020","firstPage":"0","lastPage":"0","volume":"0","journal":"ACS Catal.","title":"Mutational analysis of linalool dehydratase isomerase suggests that alcohol and alkene transformations are catalyzed using noncovalent mechanisms.","authors":["Cuetos A.","Iglesias-Fernandez J.","Danesh-Azari H.R.","Zukic E.","Dowle A.","Osuna S.","Grogan G."],"citationCrossReferences":[{"database":"DOI","id":"10.1021/acscatal.0c02958"}]}}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27062179","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5HSS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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