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5HOU

Solution Structure of p53TAD-TAZ1

Functional Information from GO Data
ChainGOidnamespacecontents
A0004402molecular_functionhistone acetyltransferase activity
A0006355biological_processregulation of DNA-templated transcription
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphoserine; by HIPK4 => ECO:0000269|PubMed:18022393
ChainResidueDetails
ASER1009

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine; by CDK5, PRPK, AMPK, NUAK1 and ATM => ECO:0000269|PubMed:10570149, ECO:0000269|PubMed:11554766, ECO:0000269|PubMed:15866171, ECO:0000269|PubMed:17108107, ECO:0000269|PubMed:17591690, ECO:0000269|PubMed:17967874, ECO:0000269|PubMed:21317932, ECO:0000269|PubMed:28842590
ChainResidueDetails
ASER1015

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Phosphothreonine; by CK1, VRK1 and VRK2 => ECO:0000269|PubMed:10606744, ECO:0000269|PubMed:10951572, ECO:0000269|PubMed:16704422
ChainResidueDetails
ATHR1018

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphoserine; by CHEK2, CK1 and PLK3 => ECO:0000269|PubMed:10570149, ECO:0000269|PubMed:11447225, ECO:0000269|PubMed:11551930, ECO:0000269|PubMed:12810724, ECO:0000269|PubMed:20041275
ChainResidueDetails
ASER1020

site_idSWS_FT_FI5
Number of Residues1
DetailsMOD_RES: Phosphoserine; by CDK5 and CDK7 => ECO:0000269|PubMed:17591690, ECO:0000269|PubMed:9372954
ChainResidueDetails
ASER1033

site_idSWS_FT_FI6
Number of Residues1
DetailsMOD_RES: Phosphoserine; by MAPKAPK5 => ECO:0000269|PubMed:17254968
ChainResidueDetails
ASER1037

site_idSWS_FT_FI7
Number of Residues1
DetailsMOD_RES: Phosphoserine; by CDK5, DYRK2, HIPK2 and PKC/PRKCG => ECO:0000269|PubMed:11740489, ECO:0000269|PubMed:11780126, ECO:0000269|PubMed:16377624, ECO:0000269|PubMed:17349958, ECO:0000269|PubMed:17591690
ChainResidueDetails
ASER1046

site_idSWS_FT_FI8
Number of Residues1
DetailsMOD_RES: Phosphothreonine; by TAF1 and GRK5 => ECO:0000269|PubMed:15053879, ECO:0000269|PubMed:20124405
ChainResidueDetails
ATHR1055

site_idSWS_FT_FI9
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:21597459
ChainResidueDetails
ALYS1024

site_idSWS_FT_FI10
Number of Residues86
DetailsZN_FING: TAZ-type 1 => ECO:0000255|PROSITE-ProRule:PRU00203
ChainResidueDetails
AASP3346-LEU3432

site_idSWS_FT_FI11
Number of Residues12
DetailsBINDING:
ChainResidueDetails
AHIS3362
ACYS3421
ACYS3426
ACYS3429
ACYS3366
ACYS3379
ACYS3384
AHIS3393
ACYS3397
ACYS3403
ACYS3408
AHIS3417

219140

PDB entries from 2024-05-01

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