Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003862 | molecular_function | 3-isopropylmalate dehydrogenase activity |
| A | 0004449 | molecular_function | isocitrate dehydrogenase (NAD+) activity |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0006102 | biological_process | isocitrate metabolic process |
| A | 0009098 | biological_process | L-leucine biosynthetic process |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue 48Y A 401 |
| Chain | Residue |
| A | THR71 |
| A | ASP218 |
| A | MN402 |
| A | HOH504 |
| A | HOH511 |
| A | SER80 |
| A | ARG86 |
| A | ARG96 |
| A | ARG111 |
| A | TYR118 |
| A | LYS163 |
| A | ASN165 |
| A | ASP194 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MN A 402 |
| Chain | Residue |
| A | ASP194 |
| A | ASP218 |
| A | 48Y401 |
| A | HOH504 |
| A | HOH511 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue IMD A 403 |
| Chain | Residue |
| A | ASP222 |
| A | ILE231 |
| A | HOH511 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue IPA A 404 |
| Chain | Residue |
| A | SER230 |
| A | GLY232 |
| A | ILE256 |
| A | ASN263 |
| A | ASP301 |
Functional Information from PROSITE/UniProt
| site_id | PS00470 |
| Number of Residues | 20 |
| Details | IDH_IMDH Isocitrate and isopropylmalate dehydrogenases signature. NLFGDIlSDl.AtvhaGSIGI |
| Chain | Residue | Details |
| A | ASN214-ILE233 | |
