Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003862 | molecular_function | 3-isopropylmalate dehydrogenase activity |
| A | 0004449 | molecular_function | isocitrate dehydrogenase (NAD+) activity |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0006102 | biological_process | isocitrate metabolic process |
| A | 0009098 | biological_process | L-leucine biosynthetic process |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue IMD A 401 |
| Chain | Residue |
| A | TYR118 |
| A | ARG133 |
| A | GLU213 |
| A | HOH598 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue IMD A 402 |
| Chain | Residue |
| A | HOH595 |
| A | GLY104 |
| A | GLU106 |
| A | LEU269 |
| A | ARG286 |
| A | ARG290 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 403 |
| Chain | Residue |
| A | PRO248 |
| A | VAL249 |
| A | HIS250 |
| A | HOH543 |
| A | HOH597 |
| A | HOH686 |
Functional Information from PROSITE/UniProt
| site_id | PS00470 |
| Number of Residues | 20 |
| Details | IDH_IMDH Isocitrate and isopropylmalate dehydrogenases signature. NLFGDIlSDl.AtvhaGSIGI |
| Chain | Residue | Details |
| A | ASN214-ILE233 | |
