Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0039694 | biological_process | viral RNA genome replication |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1001 |
| Chain | Residue |
| A | HIS712 |
| A | HIS714 |
| A | CYS728 |
| A | CYS847 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1002 |
| Chain | Residue |
| A | GLU437 |
| A | HIS441 |
| A | CYS446 |
| A | CYS449 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue LNW A 1003 |
| Chain | Residue |
| A | CYS709 |
| A | HIS711 |
| A | ARG729 |
| A | TYR766 |
| A | THR794 |
| A | SER796 |
| A | HIS798 |
| A | ALA799 |
| A | TRP803 |
| A | HOH1114 |
| A | HOH1154 |
| A | LEU511 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue LNW A 1004 |
| Chain | Residue |
| A | ARG770 |
| A | LEU774 |
| A | TYR838 |
| A | ILE851 |
| A | GLY852 |
| A | ARG856 |
| A | ARG888 |
| A | HOH1138 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 150 |
| Details | Domain: {"description":"RdRp catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00539","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Region: {"description":"Interaction with host KPNA2","evidences":[{"source":"UniProtKB","id":"P12823","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 47 |
| Details | Motif: {"description":"Bipartite nuclear localization signal","evidences":[{"source":"UniProtKB","id":"P12823","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17301146","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Site: {"description":"Important for NS5 nuclear subcellular location","evidences":[{"source":"UniProtKB","id":"P12823","evidenceCode":"ECO:0000250"}]} |
5HMW
