5HMN
Crystal structure of an aminoglycoside acetyltransferase HMB0005 from an uncultured soil metagenomic sample, unknown active site density modeled as polyethylene glycol
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008080 | molecular_function | N-acetyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| B | 0008080 | molecular_function | N-acetyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| C | 0008080 | molecular_function | N-acetyltransferase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| D | 0008080 | molecular_function | N-acetyltransferase activity |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| E | 0008080 | molecular_function | N-acetyltransferase activity |
| E | 0016740 | molecular_function | transferase activity |
| E | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| F | 0008080 | molecular_function | N-acetyltransferase activity |
| F | 0016740 | molecular_function | transferase activity |
| F | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | binding site for residue COA A 201 |
| Chain | Residue |
| A | PHE27 |
| A | ILE98 |
| A | ALA99 |
| A | THR100 |
| A | GLN121 |
| A | PRO130 |
| A | ALA131 |
| A | ALA133 |
| A | LEU134 |
| A | TYR135 |
| A | PG4202 |
| A | ASP50 |
| A | HOH324 |
| A | HOH331 |
| A | HOH332 |
| A | HOH351 |
| A | HOH372 |
| A | HOH374 |
| A | HOH381 |
| A | LEU87 |
| A | ALA88 |
| A | VAL89 |
| A | ARG94 |
| A | ARG95 |
| A | ARG96 |
| A | GLY97 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue PG4 A 202 |
| Chain | Residue |
| A | TYR33 |
| A | TYR85 |
| A | ASP86 |
| A | GLN121 |
| A | HIS146 |
| A | COA201 |
| A | HOH303 |
| A | HOH323 |
| site_id | AC3 |
| Number of Residues | 24 |
| Details | binding site for residue COA B 500 |
| Chain | Residue |
| B | PHE27 |
| B | ASP50 |
| B | LEU87 |
| B | ALA88 |
| B | VAL89 |
| B | ARG94 |
| B | ARG95 |
| B | ARG96 |
| B | GLY97 |
| B | ILE98 |
| B | ALA99 |
| B | THR100 |
| B | ALA112 |
| B | ARG113 |
| B | ASP128 |
| B | PRO130 |
| B | LEU134 |
| B | HOH612 |
| B | HOH613 |
| B | HOH614 |
| B | HOH615 |
| B | HOH628 |
| B | HOH643 |
| B | HOH688 |
| site_id | AC4 |
| Number of Residues | 23 |
| Details | binding site for residue COA C 500 |
| Chain | Residue |
| C | PHE27 |
| C | LEU87 |
| C | ALA88 |
| C | VAL89 |
| C | ARG94 |
| C | ARG95 |
| C | ARG96 |
| C | GLY97 |
| C | ILE98 |
| C | ALA99 |
| C | THR100 |
| C | GLU127 |
| C | PRO130 |
| C | ALA133 |
| C | LEU134 |
| C | TYR135 |
| C | LYS137 |
| C | HOH621 |
| C | HOH622 |
| C | HOH631 |
| C | HOH646 |
| C | HOH647 |
| C | HOH653 |
| site_id | AC5 |
| Number of Residues | 19 |
| Details | binding site for residue COA E 500 |
| Chain | Residue |
| E | HOH619 |
| E | PHE27 |
| E | GLU62 |
| E | LEU87 |
| E | VAL89 |
| E | ARG94 |
| E | ARG95 |
| E | ARG96 |
| E | GLY97 |
| E | ILE98 |
| E | ALA99 |
| E | THR100 |
| E | ASP128 |
| E | PRO130 |
| E | ALA131 |
| E | ALA133 |
| E | LEU134 |
| E | HOH601 |
| E | HOH603 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | binding site for residue COA F 500 |
| Chain | Residue |
| F | ALA26 |
| F | PHE27 |
| F | LEU87 |
| F | VAL89 |
| F | ARG94 |
| F | ARG95 |
| F | ARG96 |
| F | GLY97 |
| F | ILE98 |
| F | ALA99 |
| F | THR100 |
| F | PRO130 |
| F | LEU134 |
