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5HLE

Structural basis of backwards motion in kinesin-14: minus-end directed nKn664 in the ADP state

Functional Information from GO Data
ChainGOidnamespacecontents
A0003777molecular_functionmicrotubule motor activity
A0005524molecular_functionATP binding
A0007018biological_processmicrotubule-based movement
A0008017molecular_functionmicrotubule binding
Functional Information from PDB Data
site_idAC1
Number of Residues11
Detailsbinding site for residue ADP A 401
ChainResidue
AARG32
ALYS114
AMG402
APRO33
AGLN102
ASER104
ASER105
AGLY106
ALYS107
ATHR108
AHIS109

site_idAC2
Number of Residues2
Detailsbinding site for residue MG A 402
ChainResidue
ATHR108
AADP401

Functional Information from PROSITE/UniProt
site_idPS00411
Number of Residues12
DetailsKINESIN_MOTOR_1 Kinesin motor domain signature. GKLyLVDLAGSE
ChainResidueDetails
AGLY241-GLU252

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: BINDING => ECO:0000269|PubMed:27452403, ECO:0007744|PDB:5HLE
ChainResidueDetails
ATHR103
ASER105
AGLY106
ALYS107
ATHR108
AHIS109
ATHR110
ALEU115

226707

PDB entries from 2024-10-30

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