Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5HKK

Caldalaklibacillus thermarum F1-ATPase (wild type)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0005886	cellular_component	plasma membrane
A	0006754	biological_process	ATP biosynthetic process
A	0006811	biological_process	monoatomic ion transport
A	0015986	biological_process	proton motive force-driven ATP synthesis
A	0016020	cellular_component	membrane
A	0032559	molecular_function	adenyl ribonucleotide binding
A	0043531	molecular_function	ADP binding
A	0045259	cellular_component	proton-transporting ATP synthase complex
A	0046034	biological_process	ATP metabolic process
A	0046872	molecular_function	metal ion binding
A	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
A	1902600	biological_process	proton transmembrane transport
B	0000166	molecular_function	nucleotide binding
B	0005524	molecular_function	ATP binding
B	0005886	cellular_component	plasma membrane
B	0006754	biological_process	ATP biosynthetic process
B	0006811	biological_process	monoatomic ion transport
B	0015986	biological_process	proton motive force-driven ATP synthesis
B	0016020	cellular_component	membrane
B	0032559	molecular_function	adenyl ribonucleotide binding
B	0043531	molecular_function	ADP binding
B	0045259	cellular_component	proton-transporting ATP synthase complex
B	0046034	biological_process	ATP metabolic process
B	0046872	molecular_function	metal ion binding
B	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
B	1902600	biological_process	proton transmembrane transport
C	0000166	molecular_function	nucleotide binding
C	0005524	molecular_function	ATP binding
C	0005886	cellular_component	plasma membrane
C	0006754	biological_process	ATP biosynthetic process
C	0006811	biological_process	monoatomic ion transport
C	0015986	biological_process	proton motive force-driven ATP synthesis
C	0016020	cellular_component	membrane
C	0032559	molecular_function	adenyl ribonucleotide binding
C	0043531	molecular_function	ADP binding
C	0045259	cellular_component	proton-transporting ATP synthase complex
C	0046034	biological_process	ATP metabolic process
C	0046872	molecular_function	metal ion binding
C	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
C	1902600	biological_process	proton transmembrane transport
D	0000166	molecular_function	nucleotide binding
D	0005524	molecular_function	ATP binding
D	0005886	cellular_component	plasma membrane
D	0006754	biological_process	ATP biosynthetic process
D	0006811	biological_process	monoatomic ion transport
D	0015986	biological_process	proton motive force-driven ATP synthesis
D	0035725	biological_process	sodium ion transmembrane transport
D	0045259	cellular_component	proton-transporting ATP synthase complex
D	0046034	biological_process	ATP metabolic process
D	0046872	molecular_function	metal ion binding
D	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
D	0046962	molecular_function	sodium-transporting ATPase activity, rotational mechanism
D	1902600	biological_process	proton transmembrane transport
E	0000166	molecular_function	nucleotide binding
E	0005524	molecular_function	ATP binding
E	0005886	cellular_component	plasma membrane
E	0006754	biological_process	ATP biosynthetic process
E	0006811	biological_process	monoatomic ion transport
E	0015986	biological_process	proton motive force-driven ATP synthesis
E	0035725	biological_process	sodium ion transmembrane transport
E	0045259	cellular_component	proton-transporting ATP synthase complex
E	0046034	biological_process	ATP metabolic process
E	0046872	molecular_function	metal ion binding
E	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
E	0046962	molecular_function	sodium-transporting ATPase activity, rotational mechanism
E	1902600	biological_process	proton transmembrane transport
F	0000166	molecular_function	nucleotide binding
F	0005524	molecular_function	ATP binding
F	0005886	cellular_component	plasma membrane
F	0006754	biological_process	ATP biosynthetic process
F	0006811	biological_process	monoatomic ion transport
F	0015986	biological_process	proton motive force-driven ATP synthesis
F	0035725	biological_process	sodium ion transmembrane transport
F	0045259	cellular_component	proton-transporting ATP synthase complex
F	0046034	biological_process	ATP metabolic process
F	0046872	molecular_function	metal ion binding
F	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
F	0046962	molecular_function	sodium-transporting ATPase activity, rotational mechanism
F	1902600	biological_process	proton transmembrane transport
G	0005524	molecular_function	ATP binding
G	0005886	cellular_component	plasma membrane
G	0006754	biological_process	ATP biosynthetic process
G	0006811	biological_process	monoatomic ion transport
G	0009579	cellular_component	thylakoid
G	0015986	biological_process	proton motive force-driven ATP synthesis
G	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
G	0045259	cellular_component	proton-transporting ATP synthase complex
G	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
G	1902600	biological_process	proton transmembrane transport
H	0000166	molecular_function	nucleotide binding
H	0005524	molecular_function	ATP binding
H	0005886	cellular_component	plasma membrane
H	0006754	biological_process	ATP biosynthetic process
H	0006811	biological_process	monoatomic ion transport
H	0015986	biological_process	proton motive force-driven ATP synthesis
H	0045259	cellular_component	proton-transporting ATP synthase complex
H	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
H	1902600	biological_process	proton transmembrane transport
I	0000166	molecular_function	nucleotide binding
I	0005524	molecular_function	ATP binding
I	0005886	cellular_component	plasma membrane
I	0006754	biological_process	ATP biosynthetic process
I	0006811	biological_process	monoatomic ion transport
I	0015986	biological_process	proton motive force-driven ATP synthesis
I	0016020	cellular_component	membrane
I	0032559	molecular_function	adenyl ribonucleotide binding
I	0043531	molecular_function	ADP binding
I	0045259	cellular_component	proton-transporting ATP synthase complex
I	0046034	biological_process	ATP metabolic process
I	0046872	molecular_function	metal ion binding
I	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
I	1902600	biological_process	proton transmembrane transport
J	0000166	molecular_function	nucleotide binding
J	0005524	molecular_function	ATP binding
J	0005886	cellular_component	plasma membrane
J	0006754	biological_process	ATP biosynthetic process
J	0006811	biological_process	monoatomic ion transport
J	0015986	biological_process	proton motive force-driven ATP synthesis
J	0016020	cellular_component	membrane
J	0032559	molecular_function	adenyl ribonucleotide binding
J	0043531	molecular_function	ADP binding
J	0045259	cellular_component	proton-transporting ATP synthase complex
J	0046034	biological_process	ATP metabolic process
J	0046872	molecular_function	metal ion binding
J	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
J	1902600	biological_process	proton transmembrane transport
K	0000166	molecular_function	nucleotide binding
K	0005524	molecular_function	ATP binding
K	0005886	cellular_component	plasma membrane
K	0006754	biological_process	ATP biosynthetic process
K	0006811	biological_process	monoatomic ion transport
K	0015986	biological_process	proton motive force-driven ATP synthesis
K	0016020	cellular_component	membrane
K	0032559	molecular_function	adenyl ribonucleotide binding
K	0043531	molecular_function	ADP binding
K	0045259	cellular_component	proton-transporting ATP synthase complex
K	0046034	biological_process	ATP metabolic process
K	0046872	molecular_function	metal ion binding
K	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
K	1902600	biological_process	proton transmembrane transport
L	0000166	molecular_function	nucleotide binding
L	0005524	molecular_function	ATP binding
L	0005886	cellular_component	plasma membrane
L	0006754	biological_process	ATP biosynthetic process
L	0006811	biological_process	monoatomic ion transport
L	0015986	biological_process	proton motive force-driven ATP synthesis
L	0035725	biological_process	sodium ion transmembrane transport
L	0045259	cellular_component	proton-transporting ATP synthase complex
L	0046034	biological_process	ATP metabolic process
L	0046872	molecular_function	metal ion binding
L	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
L	0046962	molecular_function	sodium-transporting ATPase activity, rotational mechanism
L	1902600	biological_process	proton transmembrane transport
M	0000166	molecular_function	nucleotide binding
M	0005524	molecular_function	ATP binding
M	0005886	cellular_component	plasma membrane
M	0006754	biological_process	ATP biosynthetic process
M	0006811	biological_process	monoatomic ion transport
M	0015986	biological_process	proton motive force-driven ATP synthesis
M	0035725	biological_process	sodium ion transmembrane transport
M	0045259	cellular_component	proton-transporting ATP synthase complex
M	0046034	biological_process	ATP metabolic process
M	0046872	molecular_function	metal ion binding
M	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
M	0046962	molecular_function	sodium-transporting ATPase activity, rotational mechanism
M	1902600	biological_process	proton transmembrane transport
N	0000166	molecular_function	nucleotide binding
N	0005524	molecular_function	ATP binding
N	0005886	cellular_component	plasma membrane
N	0006754	biological_process	ATP biosynthetic process
N	0006811	biological_process	monoatomic ion transport
N	0015986	biological_process	proton motive force-driven ATP synthesis
N	0035725	biological_process	sodium ion transmembrane transport
N	0045259	cellular_component	proton-transporting ATP synthase complex
N	0046034	biological_process	ATP metabolic process
N	0046872	molecular_function	metal ion binding
N	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
N	0046962	molecular_function	sodium-transporting ATPase activity, rotational mechanism
N	1902600	biological_process	proton transmembrane transport
O	0005524	molecular_function	ATP binding
O	0005886	cellular_component	plasma membrane
O	0006754	biological_process	ATP biosynthetic process
O	0006811	biological_process	monoatomic ion transport
O	0009579	cellular_component	thylakoid
O	0015986	biological_process	proton motive force-driven ATP synthesis
O	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
O	0045259	cellular_component	proton-transporting ATP synthase complex
O	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
O	1902600	biological_process	proton transmembrane transport
P	0000166	molecular_function	nucleotide binding
P	0005524	molecular_function	ATP binding
P	0005886	cellular_component	plasma membrane
P	0006754	biological_process	ATP biosynthetic process
P	0006811	biological_process	monoatomic ion transport
P	0015986	biological_process	proton motive force-driven ATP synthesis
P	0045259	cellular_component	proton-transporting ATP synthase complex
P	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
P	1902600	biological_process	proton transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue ADP A 601

Chain	Residue
A	GLN172
A	MG602
A	HOH702
A	HOH709
A	THR173
A	GLY174
A	LYS175
A	THR176
A	THR177
A	PHE349
A	GLN422
A	GLU424

site_id	AC2
Number of Residues	6
Details	binding site for residue MG A 602

Chain	Residue
A	THR176
A	ADP601
A	HOH702
A	HOH709
A	HOH712
A	HOH717

site_id	AC3
Number of Residues	9
Details	binding site for residue GOL A 603

Chain	Residue
A	GLY282
A	ARG283
A	TYR286
A	PRO287
A	GLY288
A	TYR329
E	SER255
E	GLY269
E	HOH618

site_id	AC4
Number of Residues	13
Details	binding site for residue ADP B 600

Chain	Residue
B	GLN172
B	THR173
B	GLY174
B	LYS175
B	THR176
B	THR177
B	PHE349
B	GLN422
B	GLU424
B	MG601
B	HOH701
B	HOH715
B	HOH717

site_id	AC5
Number of Residues	6
Details	binding site for residue MG B 601

Chain	Residue
B	THR176
B	ADP600
B	HOH701
B	HOH714
B	HOH715
B	HOH717

site_id	AC6
Number of Residues	13
Details	binding site for residue ADP C 600

Chain	Residue
C	GLN172
C	THR173
C	GLY174
C	LYS175
C	THR176
C	THR177
C	PHE349
C	ARG354
C	GLN422
C	GLU424
C	MG601
C	HOH712
F	TYR357

site_id	AC7
Number of Residues	6
Details	binding site for residue MG C 601

Chain	Residue
C	THR176
C	ADP600
C	HOH710
C	HOH712
C	HOH718
C	HOH721

site_id	AC8
Number of Residues	19
Details	binding site for residue ADP D 600

Chain	Residue
C	VAL363
C	ARG365
D	GLY152
D	GLY154
D	VAL155
D	GLY156
D	LYS157
D	THR158
D	VAL159
D	TYR334
D	PHE407
D	ALA410
D	PHE413
D	THR414
D	MG601
D	HOH702
D	HOH717
D	HOH726
D	HOH727

site_id	AC9
Number of Residues	8
Details	binding site for residue MG D 601

Chain	Residue
D	THR158
D	GLU183
D	ARG184
D	ADP600
D	HOH702
D	HOH712
D	HOH714
D	HOH717

site_id	AD1
Number of Residues	10
Details	binding site for residue ADP E 501

Chain	Residue
E	TYR334
E	HOH615
E	HOH624
E	GLY152
E	GLY154
E	VAL155
E	GLY156
E	LYS157
E	THR158
E	VAL159

site_id	AD2
Number of Residues	6
Details	binding site for residue PO4 E 502

Chain	Residue
A	ARG365
E	LYS157
E	ARG184
E	ASP245
E	ASN246
E	ARG249

site_id	AD3
Number of Residues	14
Details	binding site for residue ADP F 600

Chain	Residue
B	ARG365
F	GLY154
F	VAL155
F	GLY156
F	LYS157
F	THR158
F	VAL159
F	TYR334
F	PHE407
F	MG601
F	HOH711
F	HOH713
F	HOH719
F	HOH724

site_id	AD4
Number of Residues	6
Details	binding site for residue MG F 601

Chain	Residue
F	THR158
F	ADP600
F	HOH708
F	HOH711
F	HOH718
F	HOH725

site_id	AD5
Number of Residues	5
Details	binding site for residue MG G 601

Chain	Residue
H	ATP201
H	HOH701
H	HOH702
H	HOH704
H	HOH705

site_id	AD6
Number of Residues	15
Details	binding site for residue ATP H 201

Chain	Residue
G	SER145
G	THR147
G	MG601
H	THR81
H	GLU83
H	GLU87
H	ILE88
H	ASP89
H	ARG92
H	ARG99
H	ARG123
H	ARG127
H	HOH701
H	HOH702
H	HOH704

site_id	AD7
Number of Residues	13
Details	binding site for residue ADP I 600

Chain	Residue
I	GLN172
I	THR173
I	GLY174
I	LYS175
I	THR176
I	THR177
I	PHE349
I	ARG354
I	GLN422
I	GLU424
I	MG601
I	HOH703
I	HOH709

site_id	AD8
Number of Residues	6
Details	binding site for residue MG I 601

Chain	Residue
I	THR176
I	ADP600
I	HOH703
I	HOH709
I	HOH711
I	HOH712

site_id	AD9
Number of Residues	14
Details	binding site for residue ADP J 600

Chain	Residue
J	GLN172
J	THR173
J	GLY174
J	LYS175
J	THR176
J	THR177
J	PHE349
J	ARG354
J	GLN422
J	GLU424
J	MG601
J	HOH702
J	HOH708
J	HOH710

site_id	AE1
Number of Residues	6
Details	binding site for residue MG J 601

Chain	Residue
J	THR176
J	ADP600
J	HOH702
J	HOH708
J	HOH709
J	HOH710

site_id	AE2
Number of Residues	13
Details	binding site for residue ADP K 600

Chain	Residue
K	GLN172
K	GLY174
K	LYS175
K	THR176
K	THR177
K	PHE349
K	ARG354
K	GLN422
K	GLU424
K	MG601
K	HOH716
K	HOH717
N	TYR357

site_id	AE3
Number of Residues	6
Details	binding site for residue MG K 601

Chain	Residue
K	THR176
K	ADP600
K	HOH715
K	HOH716
K	HOH717
K	HOH719

site_id	AE4
Number of Residues	19
Details	binding site for residue ADP L 600

Chain	Residue
K	VAL363
K	ARG365
L	GLY154
L	VAL155
L	GLY156
L	LYS157
L	THR158
L	VAL159
L	GLU187
L	TYR334
L	PHE407
L	ALA410
L	PHE413
L	THR414
L	MG601
L	HOH701
L	HOH711
L	HOH720
L	HOH726

site_id	AE5
Number of Residues	7
Details	binding site for residue MG L 601

Chain	Residue
L	THR158
L	ARG184
L	ADP600
L	HOH701
L	HOH715
L	HOH726
L	HOH727

site_id	AE6
Number of Residues	9
Details	binding site for residue ADP M 501

Chain	Residue
M	GLY152
M	GLY154
M	VAL155
M	GLY156
M	LYS157
M	THR158
M	VAL159
M	TYR334
M	PHE407

site_id	AE7
Number of Residues	6
Details	binding site for residue PO4 M 502

Chain	Residue
I	ARG365
M	LYS157
M	ARG184
M	ASP245
M	ASN246
M	ARG249

site_id	AE8
Number of Residues	14
Details	binding site for residue ADP N 600

Chain	Residue
J	ARG365
N	GLY154
N	VAL155
N	GLY156
N	LYS157
N	THR158
N	VAL159
N	TYR334
N	PHE407
N	MG601
N	HOH717
N	HOH719
N	HOH722
N	HOH724

site_id	AE9
Number of Residues	6
Details	binding site for residue MG N 601

Chain	Residue
N	THR158
N	ADP600
N	HOH708
N	HOH717
N	HOH722
N	HOH727

site_id	AF1
Number of Residues	5
Details	binding site for residue MG O 601

Chain	Residue
O	HOH703
P	ATP201
P	HOH301
P	HOH303
P	HOH304

site_id	AF2
Number of Residues	16
Details	binding site for residue ATP P 201

Chain	Residue
O	SER145
O	THR147
O	MG601
O	HOH703
P	THR81
P	GLU83
P	GLU87
P	ILE88
P	ASP89
P	ARG92
P	ALA96
P	ARG99
P	ARG123
P	ARG127
P	HOH301
P	HOH303

Functional Information from PROSITE/UniProt

site_id	PS00153
Number of Residues	14
Details	ATPASE_GAMMA ATP synthase gamma subunit signature. ITqEiaEivaGAnA

Chain	Residue	Details
G	ILE271-ALA284

site_id	PS00152
Number of Residues	10
Details	ATPASE_ALPHA_BETA ATP synthase alpha and beta subunits signature. PAVDPLASTS

Chain	Residue	Details
D	PRO335-SER344
A	PRO355-SER364

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)