Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004497 | molecular_function | monooxygenase activity |
A | 0005506 | molecular_function | iron ion binding |
A | 0006707 | biological_process | cholesterol catabolic process |
A | 0008395 | molecular_function | steroid hydroxylase activity |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
A | 0020037 | molecular_function | heme binding |
A | 0036199 | molecular_function | cholest-4-en-3-one 26-monooxygenase activity |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 24 |
Details | binding site for residue HEM A 401 |
Chain | Residue |
A | TYR63 |
A | THR232 |
A | THR233 |
A | ILE278 |
A | ARG280 |
A | ASN330 |
A | PHE331 |
A | GLY332 |
A | HIS336 |
A | CYS338 |
A | VAL339 |
A | LEU72 |
A | GLY340 |
A | LEU343 |
A | ALA344 |
A | HOH545 |
A | HOH641 |
A | VAL73 |
A | HIS80 |
A | ARG84 |
A | THR224 |
A | LEU225 |
A | GLY228 |
A | SER229 |
site_id | AC2 |
Number of Residues | 6 |
Details | binding site for residue MG A 402 |
Chain | Residue |
A | HOH540 |
A | HOH562 |
A | HOH652 |
A | HOH657 |
A | HOH691 |
A | HOH708 |
Functional Information from PROSITE/UniProt
site_id | PS00086 |
Number of Residues | 10 |
Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGgGLHYCVG |
Chain | Residue | Details |
A | PHE331-GLY340 | |