5HH0
Crystal structure of human Naa60 in complex with CoA
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 31 |
| Details | binding site for residue COA A 201 |
| Chain | Residue |
| A | TRP33 |
| A | GLY111 |
| A | GLY113 |
| A | SER114 |
| A | ASN143 |
| A | THR145 |
| A | PHE149 |
| A | ASN152 |
| A | ARG153 |
| A | ILE167 |
| A | HOH301 |
| A | PHE34 |
| A | HOH323 |
| A | HOH326 |
| A | HOH334 |
| A | HOH342 |
| A | HOH344 |
| A | HOH353 |
| A | HOH358 |
| A | HOH386 |
| A | HOH397 |
| A | HOH435 |
| A | SER100 |
| A | HOH442 |
| A | HOH454 |
| A | LEU101 |
| A | GLY102 |
| A | VAL103 |
| A | ARG108 |
| A | LYS109 |
| A | HIS110 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 191 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:25732826 |
| Chain | Residue | Details |
| A | MET1-ASP192 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000269|PubMed:27320834, ECO:0000269|PubMed:27550639 |
| Chain | Residue | Details |
| A | TYR97 | |
| A | HIS138 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:27320834, ECO:0000312|PDB:5ICV, ECO:0000312|PDB:5ICW |
| Chain | Residue | Details |
| A | TYR38 | |
| A | LEU99 | |
| A | TYR165 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:27320834, ECO:0000269|PubMed:27550639, ECO:0000312|PDB:5HGZ, ECO:0000312|PDB:5HH0, ECO:0000312|PDB:5HH1, ECO:0000312|PDB:5ICV, ECO:0000312|PDB:5ICW |
| Chain | Residue | Details |
| A | LEU101 | |
| A | LYS109 | |
| A | ASN143 | |
| A | TYR150 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | SITE: Required to position thioacetyl group => ECO:0000269|PubMed:27550639 |
| Chain | Residue | Details |
| A | PHE34 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | MOD_RES: N6-acetyllysine; by autocatalysis => ECO:0000269|PubMed:21981917 |
| Chain | Residue | Details |
| A | LYS79 | |
| A | LYS105 | |
| A | LYS156 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-acetyllysine; by autocatalysis => ECO:0000305|PubMed:21981917 |
| Chain | Residue | Details |
| A | LYS109 | |
| A | LYS121 |
