5HEB
The third PDZ domain from the synaptic protein PSD-95 in complex with a C-terminal peptide derived from CRIPT
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 501 |
| Chain | Residue |
| A | ILE341 |
| A | HOH651 |
| A | LEU353 |
| A | ARG354 |
| A | ALA402 |
| A | ASN403 |
| A | THR414 |
| A | ASP415 |
| A | HOH630 |
| A | HOH638 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 101 |
| Chain | Residue |
| A | GLY322 |
| A | GLU373 |
| A | GLN374 |
| B | SER8 |
| B | HOH201 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 80 |
| Details | Domain: {"description":"PDZ 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00143","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Region: {"description":"Sufficient for interaction with DLG4","evidences":[{"source":"PubMed","id":"9581762","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Region: {"description":"PDZ3-binding"} |
| Chain | Residue | Details |
