5HD6

High resolution structure of 3-hydroxydecanoyl-(acyl carrier protein) dehydratase from Yersinia pestis at 1.35 A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006633	biological_process	fatty acid biosynthetic process
A	0006636	biological_process	unsaturated fatty acid biosynthetic process
A	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
A	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006633	biological_process	fatty acid biosynthetic process
B	0006636	biological_process	unsaturated fatty acid biosynthetic process
B	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
B	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006633	biological_process	fatty acid biosynthetic process
C	0006636	biological_process	unsaturated fatty acid biosynthetic process
C	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
C	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006633	biological_process	fatty acid biosynthetic process
D	0006636	biological_process	unsaturated fatty acid biosynthetic process
D	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
D	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006633	biological_process	fatty acid biosynthetic process
E	0006636	biological_process	unsaturated fatty acid biosynthetic process
E	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
E	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006633	biological_process	fatty acid biosynthetic process
F	0006636	biological_process	unsaturated fatty acid biosynthetic process
F	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
F	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006633	biological_process	fatty acid biosynthetic process
G	0006636	biological_process	unsaturated fatty acid biosynthetic process
G	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
G	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006633	biological_process	fatty acid biosynthetic process
H	0006636	biological_process	unsaturated fatty acid biosynthetic process
H	0019171	molecular_function	(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
H	0034017	molecular_function	trans-2-decenoyl-acyl-carrier-protein isomerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue GOL A 201

Chain	Residue
A	MSE78
G	GOL202
A	GLY80
A	GLY116
A	GLN117
A	TYR156
A	HOH322
G	ARG105
G	ALA106
G	PHE172

---

site_id	AC2
Number of Residues	10
Details	binding site for residue GOL B 201

Chain	Residue
B	MSE78
B	GLY80
B	GLY116
B	GLN117
B	TYR156
B	HOH315
B	HOH322
F	ARG105
F	ALA106
F	PHE172

---

site_id	AC3
Number of Residues	10
Details	binding site for residue GOL C 201

Chain	Residue
C	MSE78
C	GLY80
C	GLY116
C	GLN117
C	TYR156
C	HOH319
E	ARG105
E	ALA106
E	PHE172
E	HOH303

---

site_id	AC4
Number of Residues	6
Details	binding site for residue GOL C 202

Chain	Residue
C	LYS138
C	LEU165
C	LYS167
C	ASP168
C	HOH303
C	HOH361

---

site_id	AC5
Number of Residues	9
Details	binding site for residue GOL C 203

Chain	Residue
C	ARG105
C	ALA106
E	MSE78
E	PRO79
E	GLY80
E	GLY116
E	GLN117
E	TYR156
E	HOH328

---

site_id	AC6
Number of Residues	6
Details	binding site for residue GOL D 201

Chain	Residue
D	ARG133
D	ASP160
D	LYS162
D	HOH305
H	LYS10
H	GLU11

---

site_id	AC7
Number of Residues	10
Details	binding site for residue GOL D 202

Chain	Residue
D	MSE78
D	GLY80
D	GLY116
D	GLN117
D	TYR156
D	HOH318
H	ARG105
H	ALA106
H	PHE172
H	GOL202

---

site_id	AC8
Number of Residues	8
Details	binding site for residue GOL E 201

Chain	Residue
C	PHE72
E	PRO30
E	TRP88
E	GLN89
E	GLY104
E	HOH303
E	HOH318
E	HOH337

---

site_id	AC9
Number of Residues	9
Details	binding site for residue GOL F 201

Chain	Residue
B	ARG105
B	ALA106
B	HOH448
F	MSE78
F	GLY80
F	GLY116
F	GLN117
F	TYR156
F	HOH329

---

site_id	AD1
Number of Residues	7
Details	binding site for residue GOL F 202

Chain	Residue
B	PHE72
B	HOH315
F	TRP88
F	GLN89
F	VAL163
F	HOH334
F	HOH356

---

site_id	AD2
Number of Residues	8
Details	binding site for residue GOL G 201

Chain	Residue
A	ARG105
A	ALA106
G	MSE78
G	GLY80
G	GLY116
G	GLN117
G	TYR156
G	HOH338

---

site_id	AD3
Number of Residues	11
Details	binding site for residue GOL G 202

Chain	Residue
G	GLY104
G	ARG105
G	ALA106
G	HOH307
G	HOH311
A	PHE72
A	GOL201
G	PRO30
G	ASP85
G	TRP88
G	GLN89

---

site_id	AD4
Number of Residues	9
Details	binding site for residue GOL H 201

Chain	Residue
D	ARG105
D	ALA106
H	MSE78
H	GLY80
H	GLY116
H	GLN117
H	TYR156
H	HOH329
H	HOH412

---

site_id	AD5
Number of Residues	6
Details	binding site for residue GOL H 202

Chain	Residue
D	PHE72
D	GOL202
H	TRP88
H	ALA106
H	HOH321
H	HOH345

---

site_id	AD6
Number of Residues	9
Details	binding site for residue GOL H 203

Chain	Residue
H	LYS10
H	GLY32
H	LEU35
H	ASP38
H	LEU59
H	LEU65
H	HOH333
H	HOH359
H	HOH368

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00405","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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