5HC2

Structure of esterase Est22 mutant-S188A with p-nitrophenol

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016787	molecular_function	hydrolase activity
B	0016787	molecular_function	hydrolase activity
C	0016787	molecular_function	hydrolase activity
D	0016787	molecular_function	hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue NPO A 401

Chain	Residue
A	LEU24
A	IMD402
A	GLY107
A	GLY108
A	GLY109
A	ALA188
A	GLY189
A	TYR219
A	LEU240
A	LEU242

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site_id	AC2
Number of Residues	7
Details	binding site for residue IMD A 402

Chain	Residue
A	LEU113
A	TYR120
A	GLU187
A	ALA188
A	HIS317
A	NPO401
A	IMD403

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site_id	AC3
Number of Residues	3
Details	binding site for residue IMD A 403

Chain	Residue
A	MET22
A	LEU24
A	IMD402

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site_id	AC4
Number of Residues	9
Details	binding site for residue NPO B 401

Chain	Residue
B	GLY25
B	GLY108
B	GLY109
B	ALA188
B	GLY189
B	TYR219
B	LEU240
B	LEU242
B	IMD402

---

site_id	AC5
Number of Residues	7
Details	binding site for residue IMD B 402

Chain	Residue
B	LEU24
B	LEU113
B	TYR120
B	ALA188
B	HIS317
B	ILE321
B	NPO401

---

site_id	AC6
Number of Residues	9
Details	binding site for residue NPO C 401

Chain	Residue
C	GLY25
C	GLY108
C	GLY109
C	ALA188
C	GLY189
C	TYR219
C	LEU240
C	LEU242
C	IMD402

---

site_id	AC7
Number of Residues	8
Details	binding site for residue IMD C 402

Chain	Residue
C	LEU113
C	TYR120
C	GLU187
C	ALA188
C	HIS317
C	ILE321
C	NPO401
C	HOH644

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site_id	AC8
Number of Residues	9
Details	binding site for residue NPO D 401

Chain	Residue
D	LEU24
D	GLY108
D	GLY109
D	ALA188
D	GLY189
D	TYR219
D	LEU240
D	LEU242
D	IMD402

---

site_id	AC9
Number of Residues	5
Details	binding site for residue IMD D 402

Chain	Residue
D	LEU113
D	TYR120
D	ALA188
D	HIS317
D	NPO401

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