5HA1
Crystal structure of human cellular retinol binding protein 1 in complex with retinylamine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002138 | biological_process | retinoic acid biosynthetic process |
| A | 0005501 | molecular_function | retinoid binding |
| A | 0005504 | molecular_function | fatty acid binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005811 | cellular_component | lipid droplet |
| A | 0005829 | cellular_component | cytosol |
| A | 0006776 | biological_process | vitamin A metabolic process |
| A | 0008289 | molecular_function | lipid binding |
| A | 0015908 | biological_process | fatty acid transport |
| A | 0016918 | molecular_function | retinal binding |
| A | 0019841 | molecular_function | retinol binding |
| A | 0055088 | biological_process | lipid homeostasis |
| A | 1904768 | molecular_function | all-trans-retinol binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue RNE A 201 |
| Chain | Residue |
| A | LEU20 |
| A | MET119 |
| A | LEU29 |
| A | LYS40 |
| A | ILE51 |
| A | GLY76 |
| A | ILE77 |
| A | TRP106 |
| A | GLN108 |
| A | LEU117 |
Functional Information from PROSITE/UniProt
| site_id | PS00214 |
| Number of Residues | 18 |
| Details | FABP Cytosolic fatty-acid binding proteins signature. GYWkMlvNeNFEeYLRAL |
| Chain | Residue | Details |
| A | GLY6-LEU23 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:26900151, ECO:0007744|PDB:5H8T, ECO:0007744|PDB:5HBS, ECO:0007744|PDB:5LJB, ECO:0007744|PDB:5LJC |
| Chain | Residue | Details |
| A | LYS40 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28057518, ECO:0007744|PDB:5LJC, ECO:0007744|PDB:5LJE |
| Chain | Residue | Details |
| A | MET62 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:26900151, ECO:0000269|PubMed:28057518, ECO:0007744|PDB:5H8T, ECO:0007744|PDB:5HBS, ECO:0007744|PDB:5LJB, ECO:0007744|PDB:5LJC, ECO:0007744|PDB:5LJD, ECO:0007744|PDB:5LJE |
| Chain | Residue | Details |
| A | GLN108 |
