5H9B

Drosophila CaMKII-wt in complex with a fragment of the Eag potassium channel and Mg2+/AMPPN

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004672	molecular_function	protein kinase activity
A	0005524	molecular_function	ATP binding
A	0006468	biological_process	protein phosphorylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	binding site for residue AN2 A 301

Chain	Residue
A	GLY21
A	GLU97
A	GLU140
A	ASN141
A	LEU143
A	ASP157
A	MG302
A	HOH407
A	HOH413
A	LYS22
A	GLY23
A	SER26
A	VAL28
A	ALA41
A	LYS43
A	ASP91
A	VAL93

---

site_id	AC2
Number of Residues	5
Details	binding site for residue MG A 302

Chain	Residue
A	ASN141
A	ASP157
A	AN2301
A	HOH411
A	HOH413

---

site_id	AC3
Number of Residues	1
Details	binding site for residue GOL A 303

Chain	Residue
A	SER146

---

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	24
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGKGAFSIVKrCvqkstgfe..........FAAK

Chain	Residue	Details
A	LEU20-LYS43

---

site_id	PS00108
Number of Residues	13
Details	PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. VvHrDLKpeNLLL

Chain	Residue	Details
A	VAL132-LEU144

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	260
Details	Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by CaMK2","evidences":[{"source":"PubMed","id":"11980904","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---