5H8N
Structure of the human GluN1/GluN2A LBD in complex with NAM
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue GLU A 301 |
| Chain | Residue |
| A | HIS87 |
| A | HOH438 |
| A | SER113 |
| A | THR115 |
| A | ARG120 |
| A | GLY171 |
| A | SER172 |
| A | THR173 |
| A | ASP214 |
| A | HOH402 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue 5YD A 302 |
| Chain | Residue |
| A | PRO129 |
| A | PHE130 |
| A | VAL131 |
| A | GLU132 |
| A | LEU263 |
| A | VAL266 |
| A | MET271 |
| A | GLU275 |
| A | HOH424 |
| B | PRO141 |
| B | ARG248 |
| B | SER249 |
| B | GLY250 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue GLY B 302 |
| Chain | Residue |
| B | PHE93 |
| B | PRO125 |
| B | LEU126 |
| B | THR127 |
| B | ARG132 |
| B | SER180 |
| B | SER181 |
| B | ASP225 |
| B | PHE251 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:26875626, ECO:0000269|PubMed:26919761, ECO:0000269|PubMed:28105280, ECO:0007744|PDB:5H8F, ECO:0007744|PDB:5H8H, ECO:0007744|PDB:5H8N, ECO:0007744|PDB:5H8Q, ECO:0007744|PDB:5I2K, ECO:0007744|PDB:5I2N, ECO:0007744|PDB:5KCJ, ECO:0007744|PDB:5KDT, ECO:0007744|PDB:5TP9, ECO:0007744|PDB:5TPA |
| Chain | Residue | Details |
| B | PRO125 | |
| B | ARG132 | |
| B | SER181 | |
| B | ASP225 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| B | ASN49 | |
| B | ASN80 | |
| B | ASN100 | |
| B | ASN167 | |
| B | ASN264 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN45 | |
| A | ASN46 | |
| A | ASN170 |
