5H8I
Crystal structure of Medicago truncatula N-carbamoylputrescine amidohydrolase (MtCPA) in complex with N-(dihydroxymethyl)putrescine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006596 | biological_process | polyamine biosynthetic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| A | 0033388 | biological_process | putrescine biosynthetic process from arginine |
| A | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
| B | 0006596 | biological_process | polyamine biosynthetic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| B | 0033388 | biological_process | putrescine biosynthetic process from arginine |
| B | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
| C | 0006596 | biological_process | polyamine biosynthetic process |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| C | 0033388 | biological_process | putrescine biosynthetic process from arginine |
| C | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
| D | 0006596 | biological_process | polyamine biosynthetic process |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| D | 0033388 | biological_process | putrescine biosynthetic process from arginine |
| D | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
| E | 0006596 | biological_process | polyamine biosynthetic process |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| E | 0033388 | biological_process | putrescine biosynthetic process from arginine |
| E | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
| F | 0006596 | biological_process | polyamine biosynthetic process |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| F | 0033388 | biological_process | putrescine biosynthetic process from arginine |
| F | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
| G | 0006596 | biological_process | polyamine biosynthetic process |
| G | 0016787 | molecular_function | hydrolase activity |
| G | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| G | 0033388 | biological_process | putrescine biosynthetic process from arginine |
| G | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
| H | 0006596 | biological_process | polyamine biosynthetic process |
| H | 0016787 | molecular_function | hydrolase activity |
| H | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| H | 0033388 | biological_process | putrescine biosynthetic process from arginine |
| H | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
| I | 0006596 | biological_process | polyamine biosynthetic process |
| I | 0016787 | molecular_function | hydrolase activity |
| I | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| I | 0033388 | biological_process | putrescine biosynthetic process from arginine |
| I | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
| J | 0006596 | biological_process | polyamine biosynthetic process |
| J | 0016787 | molecular_function | hydrolase activity |
| J | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| J | 0033388 | biological_process | putrescine biosynthetic process from arginine |
| J | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
| K | 0006596 | biological_process | polyamine biosynthetic process |
| K | 0016787 | molecular_function | hydrolase activity |
| K | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| K | 0033388 | biological_process | putrescine biosynthetic process from arginine |
| K | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
| L | 0006596 | biological_process | polyamine biosynthetic process |
| L | 0016787 | molecular_function | hydrolase activity |
| L | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| L | 0033388 | biological_process | putrescine biosynthetic process from arginine |
| L | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
| M | 0006596 | biological_process | polyamine biosynthetic process |
| M | 0016787 | molecular_function | hydrolase activity |
| M | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| M | 0033388 | biological_process | putrescine biosynthetic process from arginine |
| M | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
| N | 0006596 | biological_process | polyamine biosynthetic process |
| N | 0016787 | molecular_function | hydrolase activity |
| N | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| N | 0033388 | biological_process | putrescine biosynthetic process from arginine |
| N | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
| O | 0006596 | biological_process | polyamine biosynthetic process |
| O | 0016787 | molecular_function | hydrolase activity |
| O | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| O | 0033388 | biological_process | putrescine biosynthetic process from arginine |
| O | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
| P | 0006596 | biological_process | polyamine biosynthetic process |
| P | 0016787 | molecular_function | hydrolase activity |
| P | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| P | 0033388 | biological_process | putrescine biosynthetic process from arginine |
| P | 0050126 | molecular_function | N-carbamoylputrescine amidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 401 |
| Chain | Residue |
| A | SER23 |
| A | THR75 |
| A | ARG78 |
| A | HOH514 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | HOH560 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 403 |
| Chain | Residue |
| A | HOH509 |
| A | TYR54 |
| A | ALA183 |
| A | ILE184 |
| A | GLY185 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue PEG A 404 |
| Chain | Residue |
| A | ASP112 |
| A | GLY113 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for residue PGE A 405 |
| Chain | Residue |
| A | ASP295 |
| A | LYS297 |
| A | HOH588 |
| A | HOH662 |
| A | HOH667 |
| A | HOH676 |
| B | LEU172 |
| B | GLN173 |
| B | GLY174 |
| B | ARG274 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 406 |
| Chain | Residue |
| A | ARG283 |
| A | ASP286 |
| A | HOH557 |
| A | HOH575 |
| A | HOH646 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 402 |
| Chain | Residue |
| A | MET273 |
| A | TRP277 |
| A | HOH637 |
| B | SER195 |
| B | HIS198 |
| B | HOH504 |
| B | HOH517 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 403 |
| Chain | Residue |
| B | GLU51 |
| B | ARG66 |
| B | HOH518 |
| B | HOH554 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue GOL C 402 |
| Chain | Residue |
| C | HIS198 |
| C | HOH506 |
| C | HOH553 |
| C | HOH592 |
| D | MET273 |
| D | TRP277 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL C 403 |
| Chain | Residue |
| C | VAL22 |
| C | SER23 |
| C | PRO74 |
| C | THR75 |
| C | ARG78 |
| C | HOH515 |
| C | HOH523 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 404 |
| Chain | Residue |
| C | ARG66 |
| C | HOH505 |
| C | HOH525 |
| C | HOH548 |
| C | HOH611 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 405 |
| Chain | Residue |
| C | ARG201 |
| C | HOH608 |
| D | GLN204 |
| D | GLU248 |
| D | ILE249 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue PGE C 406 |
| Chain | Residue |
| C | LYS84 |
| C | ASP112 |
| C | GLY113 |
| C | HOH510 |
| C | HOH773 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 407 |
| Chain | Residue |
| C | ARG283 |
| C | PRO285 |
| C | ASP286 |
| C | HOH632 |
| C | HOH674 |
| D | HOH539 |
| site_id | AD6 |
| Number of Residues | 9 |
| Details | binding site for residue GOL D 402 |
| Chain | Residue |
| C | MET273 |
| C | TRP277 |
| D | ILE193 |
| D | SER195 |
| D | HIS198 |
| D | HOH543 |
| D | HOH587 |
| D | HOH621 |
| D | HOH717 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue GOL D 403 |
| Chain | Residue |
| D | SER23 |
| D | PRO74 |
| D | THR75 |
| D | ARG78 |
| D | HOH505 |
| D | HOH544 |
| D | HOH569 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue PEG D 404 |
| Chain | Residue |
| D | LYS81 |
| D | ASP112 |
| D | GLY113 |
| D | HOH571 |
| D | HOH620 |
| site_id | AD9 |
| Number of Residues | 8 |
| Details | binding site for residue PEG D 405 |
| Chain | Residue |
| O | ARG31 |
| O | HOH702 |
| D | LYS256 |
| D | GLU257 |
| D | GLU258 |
| D | HOH679 |
| D | HOH686 |
| D | HOH709 |
| site_id | AE1 |
| Number of Residues | 8 |
| Details | binding site for residue EDO D 406 |
| Chain | Residue |
| A | HOH575 |
| A | HOH599 |
| C | VAL300 |
| D | ARG283 |
| D | PRO285 |
| D | ASP286 |
| D | HOH586 |
| D | HOH716 |
| site_id | AE2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL E 402 |
| Chain | Residue |
| E | SER195 |
| E | HIS198 |
| E | HOH505 |
| E | HOH508 |
| E | HOH519 |
| E | HOH717 |
| F | MET273 |
| F | TRP277 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL E 403 |
| Chain | Residue |
| E | MET273 |
| E | TRP277 |
| E | HOH538 |
| E | HOH565 |
| F | HIS198 |
| site_id | AE4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL E 404 |
| Chain | Residue |
| E | VAL22 |
| E | SER23 |
| E | PRO74 |
| E | THR75 |
| E | ARG78 |
| E | HOH515 |
| E | HOH569 |
| site_id | AE5 |
| Number of Residues | 2 |
| Details | binding site for residue GOL E 405 |
| Chain | Residue |
| E | ASP112 |
| E | GLY113 |
| site_id | AE6 |
| Number of Residues | 6 |
| Details | binding site for residue GOL F 402 |
| Chain | Residue |
| F | VAL22 |
| F | SER23 |
| F | THR75 |
| F | ARG78 |
| F | HOH501 |
| F | HOH505 |
| site_id | AE7 |
| Number of Residues | 8 |
| Details | binding site for residue GOL F 403 |
| Chain | Residue |
| C | ARG284 |
| D | PRO138 |
| D | GLY139 |
| E | LEU294 |
| F | PRO285 |
| F | ASP286 |
| F | HOH568 |
| F | HOH709 |
| site_id | AE8 |
| Number of Residues | 7 |
| Details | binding site for residue GOL G 402 |
| Chain | Residue |
| G | GLU257 |
| G | HOH596 |
| G | HOH599 |
| G | HOH601 |
| G | HOH652 |
| L | LEU32 |
| L | GLU258 |
| site_id | AE9 |
| Number of Residues | 2 |
| Details | binding site for residue PEG G 403 |
| Chain | Residue |
| G | GLU30 |
| G | ARG78 |
| site_id | AF1 |
| Number of Residues | 2 |
| Details | binding site for residue PGE G 404 |
| Chain | Residue |
| G | GLN147 |
| G | LYS152 |
| site_id | AF2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL H 401 |
| Chain | Residue |
| G | HIS198 |
| H | MET273 |
| H | TRP277 |
| H | HOH530 |
| site_id | AF3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL I 401 |
| Chain | Residue |
| I | SER23 |
| I | THR75 |
| I | ARG78 |
| I | HOH515 |
| I | HOH557 |
| site_id | AF4 |
| Number of Residues | 10 |
| Details | binding site for residue GOL I 402 |
| Chain | Residue |
| I | ARG283 |
| I | PRO285 |
| I | ASP286 |
| I | HOH524 |
| I | HOH601 |
| I | HOH666 |
| J | LEU294 |
| K | PRO138 |
| K | GLY139 |
| L | ARG284 |
| site_id | AF5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL J 402 |
| Chain | Residue |
| I | MET273 |
| I | TRP277 |
| J | HIS198 |
| J | HOH506 |
| J | HOH510 |
| site_id | AF6 |
| Number of Residues | 6 |
| Details | binding site for residue GOL J 403 |
| Chain | Residue |
| J | SER23 |
| J | PRO74 |
| J | THR75 |
| J | ARG78 |
| J | HOH503 |
| J | HOH529 |
| site_id | AF7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL J 404 |
| Chain | Residue |
| J | GLU51 |
| J | PHE55 |
| J | ARG66 |
| J | HOH502 |
| J | HOH556 |
| site_id | AF8 |
| Number of Residues | 11 |
| Details | binding site for residue GOL J 405 |
| Chain | Residue |
| I | ARG284 |
| I | HOH563 |
| J | PRO138 |
| J | GLY139 |
| J | HOH560 |
| J | HOH658 |
| K | LEU294 |
| L | ARG283 |
| L | PRO285 |
| L | ASP286 |
| L | HOH561 |
| site_id | AF9 |
| Number of Residues | 2 |
| Details | binding site for residue PEG J 406 |
| Chain | Residue |
| J | ILE249 |
| J | HOH715 |
| site_id | AG1 |
| Number of Residues | 5 |
| Details | binding site for residue PGE J 407 |
| Chain | Residue |
| I | ASP295 |
| J | LEU172 |
| J | GLY174 |
| J | ARG274 |
| J | PHE280 |
| site_id | AG2 |
| Number of Residues | 7 |
| Details | binding site for residue GOL K 402 |
| Chain | Residue |
| K | HIS198 |
| K | HOH509 |
| K | HOH511 |
| K | HOH559 |
| K | HOH577 |
| L | MET273 |
| L | TRP277 |
| site_id | AG3 |
| Number of Residues | 6 |
| Details | binding site for residue GOL K 403 |
| Chain | Residue |
| K | MET273 |
| K | TRP277 |
| K | HOH521 |
| K | HOH542 |
| K | HOH773 |
| L | HIS198 |
| site_id | AG4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL K 404 |
| Chain | Residue |
| K | SER23 |
| K | PRO74 |
| K | THR75 |
| K | ARG78 |
| K | HOH501 |
| K | HOH531 |
| K | HOH619 |
| site_id | AG5 |
| Number of Residues | 8 |
| Details | binding site for residue EDO K 405 |
| Chain | Residue |
| K | ARG283 |
| K | PRO285 |
| K | ASP286 |
| K | HOH615 |
| K | HOH638 |
| M | HOH608 |
| N | HOH540 |
| N | HOH681 |
| site_id | AG6 |
| Number of Residues | 7 |
| Details | binding site for residue GOL L 402 |
| Chain | Residue |
| L | SER23 |
| L | PRO74 |
| L | THR75 |
| L | ARG78 |
| L | HOH502 |
| L | HOH506 |
| L | HOH546 |
| site_id | AG7 |
| Number of Residues | 4 |
| Details | binding site for residue PEG L 403 |
| Chain | Residue |
| L | ASP112 |
| L | GLY113 |
| L | HOH567 |
| L | HOH569 |
| site_id | AG8 |
| Number of Residues | 6 |
| Details | binding site for residue NA L 404 |
| Chain | Residue |
| G | HOH596 |
| G | HOH711 |
| L | VAL260 |
| L | HOH592 |
| L | HOH593 |
| L | HOH765 |
| site_id | AG9 |
| Number of Residues | 7 |
| Details | binding site for residue GOL M 402 |
| Chain | Residue |
| M | SER195 |
| M | HIS198 |
| M | HOH507 |
| M | HOH564 |
| M | HOH770 |
| N | MET273 |
| N | TRP277 |
| site_id | AH1 |
| Number of Residues | 8 |
| Details | binding site for residue GOL M 403 |
| Chain | Residue |
| M | VAL22 |
| M | SER23 |
| M | THR75 |
| M | ARG78 |
| M | HOH509 |
| M | HOH511 |
| M | HOH526 |
| M | HOH742 |
| site_id | AH2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL N 402 |
| Chain | Residue |
| M | MET273 |
| M | TRP277 |
| N | SER195 |
| N | HIS198 |
| N | HOH501 |
| N | HOH503 |
| N | HOH510 |
| N | HOH689 |
| site_id | AH3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL N 403 |
| Chain | Residue |
| N | SER23 |
| N | THR75 |
| N | ARG78 |
| N | HOH502 |
| N | HOH542 |
| site_id | AH4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL N 404 |
| Chain | Residue |
| N | LYS81 |
| N | LYS84 |
| N | ASP112 |
| N | GLY113 |
| N | HOH598 |
| site_id | AH5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO N 405 |
| Chain | Residue |
| K | HOH565 |
| N | ARG283 |
| N | PRO285 |
| N | ASP286 |
| N | HOH530 |
| N | HOH681 |
| N | HOH738 |
| site_id | AH6 |
| Number of Residues | 7 |
| Details | binding site for residue GOL O 402 |
| Chain | Residue |
| O | SER195 |
| O | HIS198 |
| O | HOH513 |
| O | HOH534 |
| O | HOH551 |
| P | MET273 |
| P | TRP277 |
| site_id | AH7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO P 401 |
| Chain | Residue |
| P | ARG283 |
| P | PRO285 |
| P | ASP286 |
| P | HOH524 |
| P | HOH539 |
| site_id | AH8 |
| Number of Residues | 17 |
| Details | binding site for Di-peptide N2H B 401 and CYS B 158 |
| Chain | Residue |
| A | TRP277 |
| B | GLU48 |
| B | TYR54 |
| B | LYS121 |
| B | PRO125 |
| B | TYR130 |
| B | GLU132 |
| B | ILE157 |
| B | TRP159 |
| B | ASP160 |
| B | GLN161 |
| B | PRO181 |
| B | ALA183 |
| B | GLU187 |
| B | HOH555 |
| B | HOH569 |
| B | HOH603 |
| site_id | AH9 |
| Number of Residues | 17 |
| Details | binding site for Di-peptide N2H C 401 and CYS C 158 |
| Chain | Residue |
| C | GLU48 |
| C | TYR54 |
| C | LYS121 |
| C | PRO125 |
| C | TYR130 |
| C | GLU132 |
| C | ILE157 |
| C | TRP159 |
| C | ASP160 |
| C | GLN161 |
| C | PRO181 |
| C | ALA183 |
| C | GLU187 |
| C | HOH533 |
| C | HOH597 |
| D | TRP277 |
| D | HOH609 |
| site_id | AI1 |
| Number of Residues | 15 |
| Details | binding site for Di-peptide N2H D 401 and CYS D 158 |
| Chain | Residue |
| C | TRP277 |
| D | GLU48 |
| D | TYR54 |
| D | LYS121 |
| D | PRO125 |
| D | GLU132 |
| D | ILE157 |
| D | TRP159 |
| D | ASP160 |
| D | GLN161 |
| D | PRO181 |
| D | ALA183 |
| D | GLU187 |
| D | HOH607 |
| D | HOH623 |
| site_id | AI2 |
| Number of Residues | 16 |
| Details | binding site for Di-peptide N2H E 401 and CYS E 158 |
| Chain | Residue |
| E | GLU48 |
| E | TYR54 |
| E | LYS121 |
| E | PRO125 |
| E | GLU132 |
| E | ILE157 |
| E | TRP159 |
| E | ASP160 |
| E | GLN161 |
| E | PRO181 |
| E | ALA183 |
| E | GLU187 |
| E | HOH528 |
| E | HOH554 |
| F | TRP277 |
| F | HOH553 |
| site_id | AI3 |
| Number of Residues | 17 |
| Details | binding site for Di-peptide N2H F 401 and CYS F 158 |
| Chain | Residue |
| E | TRP277 |
| F | GLU48 |
| F | TYR54 |
| F | LYS121 |
| F | PRO125 |
| F | TYR130 |
| F | GLU132 |
| F | ILE157 |
| F | TRP159 |
| F | ASP160 |
| F | GLN161 |
| F | PRO181 |
| F | ALA183 |
| F | GLU187 |
| F | HOH508 |
| F | HOH586 |
| F | HOH601 |
| site_id | AI4 |
| Number of Residues | 16 |
| Details | binding site for Di-peptide N2H G 401 and CYS G 158 |
| Chain | Residue |
| G | GLU48 |
| G | TYR54 |
| G | LYS121 |
| G | PRO125 |
| G | GLU132 |
| G | ILE157 |
| G | TRP159 |
| G | ASP160 |
| G | GLN161 |
| G | PRO181 |
| G | ALA183 |
| G | GLU187 |
| G | HOH514 |
| G | HOH567 |
| H | TRP277 |
| H | HOH532 |
| site_id | AI5 |
| Number of Residues | 16 |
| Details | binding site for Di-peptide N2H J 401 and CYS J 158 |
| Chain | Residue |
| I | TRP277 |
| I | HOH549 |
| J | GLU48 |
| J | TYR54 |
| J | LYS121 |
| J | PRO125 |
| J | GLU132 |
| J | ILE157 |
| J | TRP159 |
| J | ASP160 |
| J | GLN161 |
| J | PRO181 |
| J | ALA183 |
| J | GLU187 |
| J | HOH550 |
| J | HOH566 |
| site_id | AI6 |
| Number of Residues | 17 |
| Details | binding site for Di-peptide N2H K 401 and CYS K 158 |
| Chain | Residue |
| K | GLU48 |
| K | TYR54 |
| K | LYS121 |
| K | PRO125 |
| K | TYR130 |
| K | GLU132 |
| K | ILE157 |
| K | TRP159 |
| K | ASP160 |
| K | GLN161 |
| K | PRO181 |
| K | ALA183 |
| K | GLU187 |
| K | HOH572 |
| K | HOH621 |
| K | HOH627 |
| L | TRP277 |
| site_id | AI7 |
| Number of Residues | 15 |
| Details | binding site for Di-peptide N2H L 401 and CYS L 158 |
| Chain | Residue |
| K | TRP277 |
| K | HOH639 |
| L | GLU48 |
| L | TYR54 |
| L | LYS121 |
| L | PRO125 |
| L | GLU132 |
| L | ILE157 |
| L | TRP159 |
| L | ASP160 |
| L | GLN161 |
| L | PRO181 |
| L | ALA183 |
| L | GLU187 |
| L | HOH587 |
| site_id | AI8 |
| Number of Residues | 16 |
| Details | binding site for Di-peptide N2H M 401 and CYS M 158 |
| Chain | Residue |
| M | GLU48 |
| M | TYR54 |
| M | LYS121 |
| M | PRO125 |
| M | TYR130 |
| M | GLU132 |
| M | ILE157 |
| M | TRP159 |
| M | ASP160 |
| M | GLN161 |
| M | PRO181 |
| M | ALA183 |
| M | GLU187 |
| M | HOH537 |
| N | TRP277 |
| N | HOH601 |
| site_id | AI9 |
| Number of Residues | 16 |
| Details | binding site for Di-peptide N2H N 401 and CYS N 158 |
| Chain | Residue |
| M | TRP277 |
| M | HOH576 |
| N | GLU48 |
| N | TYR54 |
| N | LYS121 |
| N | PRO125 |
| N | GLU132 |
| N | ILE157 |
| N | TRP159 |
| N | ASP160 |
| N | GLN161 |
| N | PRO181 |
| N | ALA183 |
| N | GLU187 |
| N | HOH545 |
| N | HOH563 |
| site_id | AJ1 |
| Number of Residues | 16 |
| Details | binding site for Di-peptide N2H O 401 and CYS O 158 |
| Chain | Residue |
| O | GLU48 |
| O | TYR54 |
| O | LYS121 |
| O | PRO125 |
| O | GLU132 |
| O | ILE157 |
| O | TRP159 |
| O | ASP160 |
| O | GLN161 |
| O | PRO181 |
| O | ALA183 |
| O | GLU187 |
| O | HOH526 |
| O | HOH542 |
| O | HOH625 |
| P | TRP277 |
