Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004402 | molecular_function | histone acetyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 31 |
| Details | binding site for residue 1VU A 201 |
| Chain | Residue |
| A | HIS8 |
| A | ALA86 |
| A | VAL87 |
| A | GLN92 |
| A | VAL93 |
| A | LYS94 |
| A | GLY95 |
| A | GLY97 |
| A | THR98 |
| A | THR118 |
| A | TYR119 |
| A | ALA18 |
| A | TYR123 |
| A | ALA124 |
| A | GLY126 |
| A | TYR127 |
| A | PHE128 |
| A | LYS130 |
| A | HOH313 |
| A | HOH316 |
| A | HOH338 |
| A | HOH348 |
| A | ASN19 |
| A | HOH364 |
| A | HOH373 |
| A | ARG21 |
| A | TRP25 |
| A | GLN36 |
| A | LEU37 |
| A | VAL83 |
| A | CYS85 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 202 |
| Chain | Residue |
| A | GLY3 |
| A | ASP51 |
| A | LYS53 |
| A | ARG72 |
| A | LYS149 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 203 |
| Chain | Residue |
| A | THR88 |
| A | SER89 |
| A | ASN90 |
| A | LEU114 |
| A | TYR115 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 204 |
| Chain | Residue |
| A | THR98 |
| A | ASN102 |
| A | LYS105 |
| A | LYS130 |
| A | GLN131 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue IPA A 205 |
| Chain | Residue |
| A | LYS17 |
| A | GLN77 |
| A | TYR115 |
| A | VAL139 |
| A | PRO140 |
| A | ARG143 |
| A | HOH310 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 153 |
| Details | Domain: {"description":"N-acetyltransferase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00532","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | Region: {"description":"Loop 3","evidences":[{"source":"PubMed","id":"29211711","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"27796307","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31527837","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"29211711","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5TRL","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"23142079","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 9 |
| Details | M-CSA 524 |
| Chain | Residue | Details |
| A | PHE74 | electrostatic stabiliser |
| A | PHE79 | electrostatic stabiliser |
| A | GLU81 | proton acceptor |
| A | ILE82 | electrostatic stabiliser |
| A | VAL83 | electrostatic stabiliser |
| A | CYS85 | electrostatic stabiliser |
| A | LEU117 | electrostatic stabiliser |
| A | ILE148 | electrostatic stabiliser |
| A | TYR151 | electrostatic stabiliser |
