5H81
HETEROYOHIMBINE SYNTHASE THAS2 FROM CATHARANTHUS ROSEUS - COMPLEX WITH NADP+
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0009809 | biological_process | lignin biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0045551 | molecular_function | cinnamyl-alcohol dehydrogenase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0009809 | biological_process | lignin biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0045551 | molecular_function | cinnamyl-alcohol dehydrogenase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | binding site for residue NAP A 1000 |
| Chain | Residue |
| A | ASP49 |
| A | SER227 |
| A | LYS230 |
| A | CYS265 |
| A | VAL266 |
| A | PRO267 |
| A | LEU288 |
| A | VAL290 |
| A | SER312 |
| A | ILE313 |
| A | SER314 |
| A | VAL181 |
| A | HOH1101 |
| A | HOH1107 |
| A | HOH1167 |
| A | HOH1169 |
| A | HOH1171 |
| A | HOH1178 |
| A | HOH1188 |
| A | GLY202 |
| A | PHE203 |
| A | GLY204 |
| A | ARG205 |
| A | ILE206 |
| A | SER225 |
| A | THR226 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1001 |
| Chain | Residue |
| A | CYS48 |
| A | HIS70 |
| A | GLU71 |
| A | CYS177 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1002 |
| Chain | Residue |
| A | CYS101 |
| A | CYS104 |
| A | CYS107 |
| A | CYS115 |
| site_id | AC4 |
| Number of Residues | 21 |
| Details | binding site for residue NAP B 1000 |
| Chain | Residue |
| B | VAL181 |
| B | GLY202 |
| B | PHE203 |
| B | GLY204 |
| B | ARG205 |
| B | ILE206 |
| B | SER225 |
| B | THR226 |
| B | SER227 |
| B | LYS230 |
| B | CYS265 |
| B | VAL266 |
| B | PRO267 |
| B | LEU288 |
| B | VAL290 |
| B | SER312 |
| B | ILE313 |
| B | SER314 |
| B | HOH1143 |
| B | HOH1173 |
| B | HOH1181 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1001 |
| Chain | Residue |
| B | CYS48 |
| B | HIS70 |
| B | GLU71 |
| B | CYS177 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1002 |
| Chain | Residue |
| B | CYS101 |
| B | CYS104 |
| B | CYS107 |
| B | CYS115 |
Functional Information from PROSITE/UniProt
| site_id | PS00059 |
| Number of Residues | 15 |
| Details | ADH_ZINC Zinc-containing alcohol dehydrogenases signature. GHEiMGIvteiGnkV |
| Chain | Residue | Details |
| A | GLY69-VAL83 |
